Evidence map›Paper›PMID 34054298›Full record

ArticleVascular health and risk management2021

The Usefulness of the Combination of D-Dimer and Soluble Fibrin Monomer Complex for Diagnosis of Venous Thromboembolism in Psychiatric Practice: A Prospective Study.

Masahiro Takeshima, Hiroyasu Ishikawa, Masaya Ogasawara, Munehiro Komatsu, Dai Fujiwara, Yu Itoh, Yuki Wada, Yuki Omori, Hidenobu Ohta, Kazuo Mishima

Open access · goldAbstract read
In one paragraph

Article in Vascular health and risk management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Normal Soluble Fibrin Levels Suggest a Low Probability of Pulmonary Embolism in Patients with Deep Vein Thrombosis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Masahiro TakeshimaDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan.ORCID 0000-0003-0614-7524
Hiroyasu IshikawaDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan.
Masaya OgasawaraDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan.
Munehiro KomatsuDepartment of Neuropsychiatry, Akita City Hospital, Akita, Japan.
Dai FujiwaraDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan.
Yu ItohDepartment of Neuropsychiatry, Akita City Hospital, Akita, Japan.ORCID 0000-0002-8384-8554
Yuki WadaDepartment of Radiology, Akita University Graduate School of Medicine, Akita, Japan.
Yuki OmoriDepartment of Neuropsychiatry, Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan.ORCID 0000-0003-2843-820X
Hidenobu OhtaDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan.
Kazuo MishimaDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan.ORCID 0000-0003-1182-1181
Akita University · JPAkita University Hospital · JPTokyo Metropolitan Geriatric Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeD-dimer has the advantage of excluding venous thromboembolism (VTE) due to its high sensitivity but is disadvantageous for diagnosing VTE due to its low specificity. A method to increase the usefulness of D-dimer in the diagnosis of VTE is warranted. This study aimed to investigate the usefulness of the combination of D-dimer and soluble fibrin monomer complex (SFMC), which has been suggested as a new candidate marker for VTE, in VTE diagnosis. PATIENTS AND

methodsThis prospective study in 109 subjects was performed at a psychiatric department between August 1, 2017 and December 31, 2019. Subjects' levels of D-dimer and SFMC were measured simultaneously. Plasma levels of D-dimer and SFMC were measured using NANOPIA

resultsOnly 109 of the 783 subjects without symptoms suggestive of VTE participated in the study. Out of 41 subjects with positive D-dimer results, 17 subjects were diagnosed with VTE. A receiver operating characteristic curve analysis was performed to determine cutoff values. The area under the curves was 0.848 for SFMC (

conclusionSFMC was useful for diagnosing VTE in the psychiatric patients with positive D-dimer results.

Indexed as

AgedBiomarkersFemaleFibrin Fibrinogen Degradation ProductsHumansInpatientsMaleMental DisordersMiddle AgedPredictive Value of TestsProspective StudiesPsychiatric Department, HospitalPulmonary EmbolismTomography, X-Ray ComputedVenous ThromboembolismVenous ThrombosisBiomarkersFibrin Fibrinogen Degradation Productsfibrin fragment Dfibrinmonomercomputed tomographyD-dimerpsychiatric patientssoluble fibrin monomer complexvenous thromboembolism

Identifiers

PMID34054298
PMCPMC8149348
OpenAlexW3160902801

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.