Evidence map›Paper›PMID 34054246›Full record

ArticleJournal of Ayurveda and integrative medicine

Evaluation of potency of the selected bioactive molecules from Indian medicinal plants with M

Pinku Halder, Upamanyu Pal, Pranab Paladhi, Saurav Dutta, Pallab Paul, Samudra Pal, Debasmita Das, Agnish Ganguly, Ishita Dutta, Sayarneel Mandal and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of Ayurveda and integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

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  8. Natural products can be used in therapeutic management of COVID-19: Probable mechanistic insights.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Review
  9. Paemi Sino · 2022
    Article
  10. Inhibition of the main protease of SARS-CoV-2 (MComputational and structural biotechnology journal · 2022
    Review
  11. Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Pinku HalderCytogenetics & Genomics Research Unit, Department of Zoology; University of Calcutta, Taraknath Palit Siksha Prangan (Ballygunge Science College Campus), 35 Ballygunge Circular Road, Kolkata, West Bengal, 700019, India.
Upamanyu PalCytogenetics & Genomics Research Unit, Department of Zoology; University of Calcutta, Taraknath Palit Siksha Prangan (Ballygunge Science College Campus), 35 Ballygunge Circular Road, Kolkata, West Bengal, 700019, India.
Pranab PaladhiCytogenetics & Genomics Research Unit, Department of Zoology; University of Calcutta, Taraknath Palit Siksha Prangan (Ballygunge Science College Campus), 35 Ballygunge Circular Road, Kolkata, West Bengal, 700019, India.
Saurav DuttaCytogenetics & Genomics Research Unit, Department of Zoology; University of Calcutta, Taraknath Palit Siksha Prangan (Ballygunge Science College Campus), 35 Ballygunge Circular Road, Kolkata, West Bengal, 700019, India.
Pallab PaulCytogenetics & Genomics Research Unit, Department of Zoology; University of Calcutta, Taraknath Palit Siksha Prangan (Ballygunge Science College Campus), 35 Ballygunge Circular Road, Kolkata, West Bengal, 700019, India.
Samudra PalCytogenetics & Genomics Research Unit, Department of Zoology; University of Calcutta, Taraknath Palit Siksha Prangan (Ballygunge Science College Campus), 35 Ballygunge Circular Road, Kolkata, West Bengal, 700019, India.
Debasmita DasCytogenetics & Genomics Research Unit, Department of Zoology; University of Calcutta, Taraknath Palit Siksha Prangan (Ballygunge Science College Campus), 35 Ballygunge Circular Road, Kolkata, West Bengal, 700019, India.
Agnish GangulyCytogenetics & Genomics Research Unit, Department of Zoology; University of Calcutta, Taraknath Palit Siksha Prangan (Ballygunge Science College Campus), 35 Ballygunge Circular Road, Kolkata, West Bengal, 700019, India.
Ishita DuttaCytogenetics & Genomics Research Unit, Department of Zoology; University of Calcutta, Taraknath Palit Siksha Prangan (Ballygunge Science College Campus), 35 Ballygunge Circular Road, Kolkata, West Bengal, 700019, India.
Sayarneel MandalCytogenetics & Genomics Research Unit, Department of Zoology; University of Calcutta, Taraknath Palit Siksha Prangan (Ballygunge Science College Campus), 35 Ballygunge Circular Road, Kolkata, West Bengal, 700019, India.
Anirban RayDepartment of Zoology, Bangabasi Morning College (affiliated to University of Calcutta), Kolkata, West Bengal, 700009, India.
Sujay GhoshCytogenetics & Genomics Research Unit, Department of Zoology; University of Calcutta, Taraknath Palit Siksha Prangan (Ballygunge Science College Campus), 35 Ballygunge Circular Road, Kolkata, West Bengal, 700019, India. Electronic address: sgzoo@caluniv.ac.in.
University of Calcutta · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe recent outbreak of the novel SARS-CoV-2 across the globe and the absence of specific drug against this virus lead the scientific community to look into some alternative indigenous treatments. India as a hub of Ayurvedic and medicinal plants can shed light on its treatment using specific active bio-molecules from these plants.

objectivesKeeping our herbal resources in mind, we were interested to inquire whether some phytochemicals from Indian spices and medicinal plants can be used as alternative therapeutic agents in contrast to synthetic drugs. MATERIALS AND

methodsWe used

resultsUrsolic acid showed the highest docking score (-8.7 kcal/mol) followed by hyperoside (-8.6 kcal/mol), α-Hederin (-8.5 kcal/mol) and nimbaflavone (-8.0 kcal/mol). epigallocatechin, catechins, and curcumin also exhibited high binding affinity (Docking score -7.3, -7.1 and -7.1 kcal/mol) with the M

conclusionThis finding provides a basis for biochemical assay of tested bioactive molecules on SARS-CoV-2 virus.

Indexed as

Indian spicesInsilico molecular dockingMedicinal plantsMproPhytochemicalSARS CoV-2 virus

Identifiers

PMID34054246
PMCPMC8139275
OpenAlexW3164091117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.