Evidence map›Paper›PMID 34053986›Full record

ArticleInternal medicine (Tokyo, Japan)2021

A Kidney Transplant Patient Who Died of COVID-19-associated Severe Acute Respiratory Distress Syndrome.

Akinari Tsukada, Manabu Suzuki, Yuya Kishino, Kento Misumi, Toru Igari, Noriko Nakajima, Yuko Sato, Tadaki Suzuki, Takashi Katsuno, Yusaku Kusaba and 8 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Akinari TsukadaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Manabu SuzukiDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Yuya KishinoDepartment of Diagnostic Pathology, National Center for Global Health and Medicine, Japan.
Kento MisumiDepartment of Diagnostic Pathology, National Center for Global Health and Medicine, Japan.
Toru IgariDepartment of Diagnostic Pathology, National Center for Global Health and Medicine, Japan.
Noriko NakajimaDepartment of Pathology, National Institute of Infectious Diseases, Japan.
Yuko SatoDepartment of Pathology, National Institute of Infectious Diseases, Japan.
Tadaki SuzukiDepartment of Pathology, National Institute of Infectious Diseases, Japan.
Takashi KatsunoDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Yusaku KusabaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Yoshie TsujimotoDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Keita SakamotoDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Masao HashimotoDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Junko TeradaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Jin TakasakiDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Shinyu IzumiDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Masayuki HojoDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
Haruhito SugiyamaDepartment of Respiratory Medicine, National Center for Global Health and Medicine, Japan.
National Center for Global Health and Medicine · JPNational Institute of Infectious Diseases · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a 67-year-old kidney transplant patient who died of COVID-19. He was treated with hydroxychloroquine and azithromycin and received mechanical ventilation that temporarily improved his respiratory status. Despite our efforts, however, he later developed respiratory failure and died 43 days after the disease onset. The autopsy revealed prominent organization of alveoli and alveolar ducts, with a massive accumulation of macrophages in the lungs. A few severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen-positive cells were detected in the lung, suggesting delayed virus clearance owing to his long-term immunosuppressed state, leading to constant lung damage and ultimately respiratory failure.

Indexed as

COVID-19Kidney TransplantationRespiratory Distress SyndromeAgedHumansLungMaleSARS-CoV-2Coronavirus disease 2019COVID-19immunosuppressedkidney transplantSARS-CoV-2

Identifiers

PMID34053986
PMCPMC8355385
OpenAlexW3165144112

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.