Evidence map›Paper›PMID 34053923›Full record

ArticleAnnals of hepato-biliary-pancreatic surgery2021

Adjuvant therapy using

Jong Man Kim, Sung Yoo Cho, Jinsoo Rhu, Miyoung Jung, Jung Hyun Her, Okjae Lim, Gyu-Seong Choi, Eui-Cheol Shin, Yu-Kyeong Hwang, Jae-Won Joh

Open access · diamondAbstract read
In one paragraph

Article in Annals of hepato-biliary-pancreatic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Recent Progress in Systemic Therapy for Advanced Hepatocellular Carcinoma.International journal of molecular sciences · 2024
    Review
  6. Neoadjuvant Therapy for Hepatocellular Carcinoma.Journal of hepatocellular carcinoma · 2022
    Review
  7. [The progress and challenges in immunotherapy for the difficulty- to- treat liver diseases].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jong Man KimDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-1903-8354
Sung Yoo ChoCell Therapy Research Center, GC LabCell, Yongin, Korea.ORCID https://orcid.org/0000-0001-7785-1450
Jinsoo RhuDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9809-8525
Miyoung JungCell Therapy Research Center, GC LabCell, Yongin, Korea.ORCID https://orcid.org/0000-0003-0296-3524
Jung Hyun HerCell Therapy Research Center, GC LabCell, Yongin, Korea.ORCID https://orcid.org/0000-0002-1044-2430
Okjae LimCell Therapy Research Center, GC LabCell, Yongin, Korea.ORCID https://orcid.org/0000-0002-8838-4496
Gyu-Seong ChoiDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-2545-3105
Eui-Cheol ShinLaboratory of Immunology and Infectious Diseases, Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea.ORCID https://orcid.org/0000-0002-6308-9503
Yu-Kyeong HwangCell Therapy Research Center, GC LabCell, Yongin, Korea.ORCID https://orcid.org/0000-0001-5345-6691
Jae-Won JohDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4823-6218
Cell Biotech (South Korea) · KRSamsung Medical Center · KRKorea Advanced Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUNDS/

aimsFewer reports have been published regarding hepatectomy patients with solitary hepatocellular carcinoma (HCC) who received immunotherapeutic agents as adjuvant therapy. We evaluated the safety and efficacy of

methodsFrom August 2014 to October 2015, five patients who underwent hepatic resection received

resultsThe median age of the five patients (three men and two women) was 44.8 years (range, 36-54 years). All had hepatitis B virus-related HCC, and the median tumor size was 2.2 cm (range, 2.1-8.2 cm). None of the patients had any adverse events. HCC recurrence developed in two patients at one year after hepatic resection, but four patients were alive at 3 years. The two recurrence-free patients showed a higher ratio of CD8+ T lymphocyte populations before and after administration of

conclusionsImmunotherapy using

Indexed as

EfficacyHepatocellular carcinomaImmunotherapyNatural killer cellsSafety

Identifiers

PMID34053923
PMCPMC8180393
OpenAlexW3164926219

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.