Evidence map›Paper›PMID 34053510›Full record

ReviewFertility and sterility2021

Vasectomy reversal vs. sperm retrieval with in vitro fertilization: a contemporary, comparative analysis.

Justin M Dubin, Joshua White, Jesse Ory, Ranjith Ramasamy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Fertility and sterility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Vasectomy reversal: lessons learned to optimize clinical outcomes.International journal of impotence research · 2026
    Review
  9. Vasectomy Procedures on the Rise in France From 2010 to 2022.Perspectives on sexual and reproductive health · 2025
    Article
  10. The review of the long-term health risks associated with vasectomy.International journal of impotence research · 2025
    Review
  11. Comparing vasectomy techniques, recovery and complications: tips and tricks.International journal of impotence research · 2025
    Review
  12. Article
  13. Review
  14. Review
  15. Vasectomy Regret or Lack Thereof.Health psychology research · 2022
    Article
  16. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Justin M DubinDepartment of Urology, University of Miami Miller School of Medicine, Miami, Florida. Electronic address: jdubin50@gmail.com.
Joshua WhiteDepartment of Urology, Dalhousie University, Halifax, Nova Scotia.
Jesse OryDepartment of Urology, University of Miami Miller School of Medicine, Miami, Florida.
Ranjith RamasamyDepartment of Urology, University of Miami Miller School of Medicine, Miami, Florida.
University of Miami · USDalhousie University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the primary options available to men who desire fertility after a vasectomy.

designLiterature review.

settingUniversity of Miami Miller School of Medicine. PATIENT(S): Men with a previous vasectomy now seeking fertility. INTERVENTION(S): The two main options to achieve paternity for men following vasectomy include vasectomy reversal (VR) and surgical sperm retrieval with subsequent in vitro fertilization (IVF). MAIN OUTCOME MEASURE(S): We reviewed and compared the important considerations for men deciding between these 2 options, including: obstructive interval, female partner age, antisperm antibodies, male partner age, female infertility factors, and cost. RESULT(S): Both VR and IVF represent reasonable options for the couple seeking fertility after vasectomy. Specific circumstances may favor one modality over another, depending on obstructive interval, possible female fertility factors, female partner age, male partner age, and cost. In the absence of insurance coverage, VR is often more cost-effective than IVF. Alternatively, when a female factor may contribute to infertility in addition to vasectomy, IVF is often the better choice. Antisperm antibodies are unlikely to contribute to infertility following a successful VR. CONCLUSION(S): VR or surgical sperm retrieval with IVF are reasonable options for couples seeking children after vasectomy. Pregnancy rates for both options are overall similar, so prior to pursuing either option, a thorough discussion with a reproductive urologist who possesses microsurgical skills in VR and a reproductive endocrinologist with expertise in IVF is imperative. Making a final choice through shared decision-making while considering these points is ideal.

Indexed as

Fertilization in VitroSperm RetrievalAdultFemaleFertilityHumansInfertility, MaleMaleMaternal AgeMiddle AgedPregnancyPregnancy RateRisk FactorsTreatment OutcomeVasectomyVasovasostomyInfertilityIVFmale infertilitysperm retrievalvasectomy reversal

Identifiers

PMID34053510
OpenAlexW3164015829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.