Evidence map›Paper›PMID 34053468›Full record

ReviewMicrobiome2021

Challenges in exploring and manipulating the human skin microbiome.

Manon Boxberger, Valérie Cenizo, Nadim Cassir, Bernard La Scola

Abstract readReviewVideo-Audio Media
In one paragraph

Review in Microbiome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pathogenic characterization and drug resistance of neonatal sepsis in China: a systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
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  15. Bacterial and fungal co-colonization altersFrontiers in microbiology · 2026
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61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manon BoxbergerIRD, AP-HM, MEPHI, Aix Marseille Université, Marseille, France.
Valérie CenizoGroupe L'Occitane, R&D Department, Zone Industrielle Saint Maurice, 4100, Manosque, Alpes-de Haute-Provence, France.
Nadim CassirIRD, AP-HM, MEPHI, Aix Marseille Université, Marseille, France.
Bernard La ScolaIRD, AP-HM, MEPHI, Aix Marseille Université, Marseille, France. bernard.la-scola@univ-amu.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skin is the exterior interface of the human body with the environment. Despite its harsh physical landscape, the skin is colonized by diverse commensal microbes. In this review, we discuss recent insights into skin microbial populations, including their composition and role in health and disease and their modulation by intrinsic and extrinsic factors, with a focus on the pathobiological basis of skin aging. We also describe the most recent tools for investigating the skin microbiota composition and microbe-skin relationships and perspectives regarding the challenges of skin microbiome manipulation. Video abstract.

Indexed as

MicrobiotaHumansSkin3D skin modelsBacteriaCosmeticsCultureDiseasesMicrobiomeNext-generation sequencingProbioticsSkin

Identifiers

PMID34053468
PMCPMC8166136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.