ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2021
The impact of testing and infection prevention and control strategies on within-hospital transmission dynamics of COVID-19 in English hospitals.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
71 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effectiveness of SARS-CoV-2 testing strategies in reducing COVID-19 cases, hospitalisations, and deaths.The Cochrane database of systematic reviews · 2025Pooled it
- The role of routine SARS-CoV-2 screening of healthcare-workers in acute care hospitals in 2020: a systematic review and meta-analysis.BMC infectious diseases · 2022Pooled it
- Informing optimal testing and isolation strategies across different stages of the diagnostic development pipeline using mathematical models: SARS-CoV-2 in the UK as a case study.BMJ public health · 2026Article
- The relative effectiveness of personal protective equipment and environmental controls in protecting healthcare workers from Covid-19.Annals of work exposures and health · 2025Article
- Effectiveness of SARS-CoV-2 testing strategies.The Cochrane database of systematic reviews · 2025Article
- Mapping the viral battlefield: SARS-CoV-2 infection dynamics among healthcare workers in Brazil.Human resources for health · 2025Article
- Dynamic contagion potential framework for optimizing infection control in healthcare.Frontiers in public health · 2025Article
- Exploring optimal control strategies in a nonlinear fractional bi-susceptible model for Covid-19 dynamics using Atangana-Baleanu derivative.Scientific reports · 2024Article
- Contextual Hospital Conditions and the Risk of Nosocomial SARS-CoV-2 Infection: A Matched Case-Control Study with Density Sampling in a Large Portuguese Hospital.Journal of clinical medicine · 2024Article
- COVID-19-related temporary disability in healthcare workers in Spain during the four first pandemic waves.Preventive medicine reports · 2024Article
- COVID-19 transmission and control in land public transport: A literature review.Fundamental research · 2024Review
- The multi-dimensional challenges of controlling respiratory virus transmission in indoor spaces: Insights from the linkage of a microscopic pedestrian simulation and SARS-CoV-2 transmission model.PLoS computational biology · 2024Article
- Infectious Disease in the Workplace: Quantifying Uncertainty in Transmission.Bulletin of mathematical biology · 2024Article
- The effectiveness and efficiency of asymptomatic SARS-CoV-2 testing strategies for patient and healthcare workers within acute NHS hospitals during an omicron-like period.BMC infectious diseases · 2024Article
- Sorting out assortativity: When can we assess the contributions of different population groups to epidemic transmission?PloS one · 2024Article
- Protecting healthcare workers and patients during the COVID-19 pandemic: a comparison of baseline and follow-up infection prevention and control needs in Nigerian military healthcare facilities delivering HIV services.BMC health services research · 2023Article
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- Nosocomial SARS-CoV-2 Infections and Mortality During Unique COVID-19 Epidemic Waves.JAMA network open · 2023Article
- Article
- Cardiovascular surgery during the first wave of COVID-19 pandemic.Turk gogus kalp damar cerrahisi dergisi · 2023Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Nosocomial transmission of SARS-CoV-2 is a key concern, and evaluating the effect of testing and infection prevention and control strategies is essential for guiding policy in this area. Using a within-hospital SEIR transition model of SARS-CoV-2 in a typical English hospital, we estimate that between 9 March 2020 and 17 July 2020 approximately 20% of infections in inpatients, and 73% of infections in healthcare workers (HCWs) were due to nosocomial transmission. Model results suggest that placing suspected COVID-19 patients in single rooms or bays has the potential to reduce hospital-acquired infections in patients by up to 35%. Periodic testing of HCWs has a smaller effect on the number of hospital-acquired COVID-19 cases in patients, but reduces infection in HCWs by as much as 37% and results in only a small proportion of staff absences (approx. 0.3% per day). This is considerably less than the 20-25% of staff that have been reported to be absent from work owing to suspected COVID-19 and self-isolation. Model-based evaluations of interventions, informed by data collected so far, can help to inform policy as the pandemic progresses and help prevent transmission in the vulnerable hospital population. This article is part of the theme issue 'Modelling that shaped the early COVID-19 pandemic response in the UK'.
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