Evidence map›Paper›PMID 34052963›Full record

ArticleCommunity mental health journal2022

A Comparison of Attitudes, Comfort, and Knowledge of Clozapine Among Two Diverse Samples of US Psychiatrists.

Robert O Cotes, A Umair Janjua, Beth Broussard, David Lazris, Ayesha Khan, Yunshen Jiao, Sarah L Kopelovich, David R Goldsmith

Abstract read
In one paragraph

Article in Community mental health journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robert O CotesDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 10 Park Place, Suite 620, Atlanta, GA, 30303, USA. robert.o.cotes@emory.edu.ORCID http://orcid.org/0000-0001-9903-8807
A Umair JanjuaDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 10 Park Place, Suite 620, Atlanta, GA, 30303, USA.
Beth BroussardDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 10 Park Place, Suite 620, Atlanta, GA, 30303, USA.
David LazrisDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 10 Park Place, Suite 620, Atlanta, GA, 30303, USA.
Ayesha KhanSchool of Medicine, American University of Integrative Sciences, Bridgetown, Barbados.
Yunshen JiaoEmory University Rollins School of Public Health, Atlanta, GA, USA.
Sarah L KopelovichDepartment of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
David R GoldsmithDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 10 Park Place, Suite 620, Atlanta, GA, 30303, USA.

Funding

Impact of Inflammation on Reward Circuits, Motivational Deficits and Negative Symptoms in SchizophreniaK23MH114037 · NIMH · EMORY UNIVERSITY · PI GOLDSMITH, DAVID RYAN · 2018 to 2022
$957k
NIMH NIH HHS K23 MH114037NIMH NIH HHS L30 MH114414
6 · The paper itself

Abstract

Considerable variation in clozapine utilization exists across the United States, and little is known about the perspective of psychiatrists in states with low clozapine use. To better understand clozapine practices, attitudes, and barriers, a survey was administered to a group of southeastern state conference attendees (SSCA; N = 86). The same survey was administered to psychiatrists belonging to a national community psychiatry organization (AACP; N = 57), and differences were analyzed across the two samples. In comparison to the AACP, the SSCA group felt less comfortable, perceived clozapine as less safe and effective, had fewer patients on clozapine, and were more likely to prefer antipsychotic polypharmacy to clozapine use. Across the sample, use of a myocarditis screening protocol was rare (N = 14/76; 18%) and less than half used plasma antipsychotic levels to guide dosage (N = 60/129; 47%). Continuing professional education on clozapine are needed for psychiatrists who see individuals with psychotic disorders.

Indexed as

Antipsychotic AgentsClozapinePsychiatryAttitude of Health PersonnelHumansPolypharmacyUnited StatesAntipsychotic AgentsClozapineAttitudesClozapinePrescriberSchizophrenia

Identifiers

PMID34052963
PMCPMC9112232

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.