Evidence map›Paper›PMID 34052933›Full record

ArticleEsophagus : official journal of the Japan Esophageal Society2021

Peri-anastomotic microdialysis lactate assessment after esophagectomy.

Jakob Hedberg, Gustav Linder, Magnus Sundbom

Open access · hybridAbstract read
In one paragraph

Article in Esophagus : official journal of the Japan Esophageal Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Frontiers in surgery · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jakob HedbergDepartment of Surgical Sciences, Uppsala University, 75185 Akademiska Sjukhuset, Uppsala, Sweden. Jakob.hedberg@surgsci.uu.se.ORCID 0000-0003-1308-4592
Gustav LinderDepartment of Surgical Sciences, Uppsala University, 75185 Akademiska Sjukhuset, Uppsala, Sweden.
Magnus SundbomDepartment of Surgical Sciences, Uppsala University, 75185 Akademiska Sjukhuset, Uppsala, Sweden.
Uppsala University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEsophagectomy is the cornerstone in curative treatment for esophageal and gastroesophageal junctional cancer. Esophageal resection is an advanced procedure with many complications, whereof anastomotic leak is the most dreaded. This study aimed to monitor the microcirculation with microdialysis analysis of local lactate levels in real-time on both sides of the esophagogastric anastomosis in totally minimally invasive Ivor-Lewis esophagectomy. MATERIALS AND

methodsTwenty-five patients planned for esophageal resection with gastric conduit reconstruction and intrathoracic anastomosis were recruited. A sampling device, the OnZurf

resultsAll probes could be positioned as planned and on the third postoperative day 19/25 and 15/25 of the esophageal and gastric probes, respectively, continued to deliver measurements. In total, 89.6% (1539/1718) and 72.4% (1098/1516) of the measurements were deemed successful. The average lactate level on the esophageal side of the anastomosis and the gastric conduit ranged between 1.1-11.5 and 0.8-7.0 mM, respectively. Two anastomotic leaks occurred, one of which had persisting high lactate levels on the gastric side of the anastomosis.

conclusionApplication and use of the novel CliniSenz

Indexed as

EsophagectomyLactic AcidAnastomosis, SurgicalHumansMicrodialysisPostoperative ComplicationsLactic AcidAnastomotic leakEsophagusMicrodialysis

Identifiers

PMID34052933
PMCPMC8387264
OpenAlexW3165380741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.