Evidence map›Paper›PMID 34052917›Full record

ArticleEuropean journal of nutrition2021

Magnesium supplementation alleviates corticosteroid-associated muscle atrophy in rats.

Lizhen Zheng, Le Huang, Ziyi Chen, Can Cui, Ri Zhang, Ling Qin

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Lizhen ZhengMusculoskeletal Research Laboratory of Department of Orthopaedics and Traumatology and Innovative Orthopaedic Biomaterial and Drug Translational Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Rm74026, 5/F, Clinical Science Building, Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China.ORCID http://orcid.org/0000-0003-2135-7079
Le HuangMusculoskeletal Research Laboratory of Department of Orthopaedics and Traumatology and Innovative Orthopaedic Biomaterial and Drug Translational Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Rm74026, 5/F, Clinical Science Building, Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China.
Ziyi ChenMusculoskeletal Research Laboratory of Department of Orthopaedics and Traumatology and Innovative Orthopaedic Biomaterial and Drug Translational Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Rm74026, 5/F, Clinical Science Building, Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China.
Can CuiMusculoskeletal Research Laboratory of Department of Orthopaedics and Traumatology and Innovative Orthopaedic Biomaterial and Drug Translational Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Rm74026, 5/F, Clinical Science Building, Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China.
Ri ZhangMusculoskeletal Research Laboratory of Department of Orthopaedics and Traumatology and Innovative Orthopaedic Biomaterial and Drug Translational Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Rm74026, 5/F, Clinical Science Building, Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China.
Ling QinMusculoskeletal Research Laboratory of Department of Orthopaedics and Traumatology and Innovative Orthopaedic Biomaterial and Drug Translational Research Laboratory, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Rm74026, 5/F, Clinical Science Building, Prince of Wales Hospital, Shatin, Hong Kong SAR, People's Republic of China. lingqin@cuhk.edu.hk.
Chinese University of Hong Kong · HKDepartment of Health · CN

Funding

Innovation and Technology Commission - Hong Kong T13-402/17-N
6 · The paper itself

Abstract

purposeCorticosteroid (CS) therapy for infectious and rheumatological diseases showed to decrease serum magnesium (Mg

methodsTwelve 24-week-old male Sprague-Dawley rats were treated with lipopolysaccharide (LPS) and CS methylprednisolone (MPS) to induce muscle atrophy, with half of the rats also given daily 50 mg/kg Mg

resultsLPS + CS treatments induced hypomagnesemia while the serum Mg

conclusionThe current study demonstrated that Mg

Indexed as

COVID-19MagnesiumAdrenal Cortex HormonesAnimalsDietary SupplementsDisease Models, AnimalHumansMaleMuscle Fibers, SkeletalMuscle, SkeletalMuscular AtrophyRatsRats, Sprague-DawleySARS-CoV-2Adrenal Cortex HormonesMagnesiumCorticosteroidMagnesiumMuscle atrophy

Identifiers

PMID34052917
PMCPMC8164831
OpenAlexW3164562031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.