Evidence map›Paper›PMID 34052858›Full record

ArticlePediatric cardiology2021

Reliability of Fetal Echocardiography in Predicting Postnatal Critical Hypoxia in Patients with Transposition of Great Arteries and Intact Ventricular Septum.

M Masci, L Pasquini, T Alsaied, L Di Chiara, R Formigari, L Galletti, C M Campanale, A Romiti, M Bonito, P Bagolan and 1 more

Abstract read
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In one paragraph

Article in Pediatric cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

M MasciPerinatal Cardiology Unit, Department of Medical and Surgical for Fetus-Neonate, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
L PasquiniPerinatal Cardiology Unit, Department of Medical and Surgical for Fetus-Neonate, Bambino Gesù Children's Hospital IRCCS, Rome, Italy. luciano.pasquini@opbg.net.
T AlsaiedHeart Institute Department of Pediatrics, Cincinnati Children's Hospital Medical Center University of Cincinnati, Cincinnati, OH, USA.
L Di ChiaraPediatric Cardiac Intensive Care Unit, Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
R FormigariCardiac Hemodynamics Unit, Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children Hospital-IRCSS, Rome, Italy.
L GallettiPediatric Cardiac Surgery Unit, Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
C M CampanalePerinatal Cardiology Unit, Department of Medical and Surgical for Fetus-Neonate, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
A RomitiFetal Medicine and Surgery Unit, Department of Medical and Surgical for Fetus-Neonate, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
M BonitoDepartment of Obstetrics and Gynecology, San Pietro Fatebenefratelli Hospital, Rome, Italy.
P BagolanNeonatal Surgery Unit, Department of Medical and Surgical for Fetus-Neonate, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
A ToscanoPerinatal Cardiology Unit, Department of Medical and Surgical for Fetus-Neonate, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Bambino Gesù Children's Hospital · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITCincinnati Children's Hospital Medical Center · USFatebenefratelli Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Critical hypoxemia soon after birth is the most critical preoperative determinant of neurological outcomes and survival in newborns with Dextro Transposition of the Great Arteries and Intact Ventricular Septum (D-TGAIVS). Our study aimed to define fetal echocardiographic aspects that can better predict neonates with D-TGAIVS at risk for restricted interatrial communication after birth. 31 fetuses with a prenatal diagnosis of D-TGAIVS were included in our study. We divided patients with D-TGAIVS according to the timing of balloon atrial septostomy: Urgent, Not-Urgent and no BAS. We identified five fetal echocardiographic aspects of the interatrial septum (redundant, aneurysmal, flat, fixed, hypermobile). No significant differences in these fetal echocardiographic features were found between the three different groups of D-TGAIVS according to the timing of balloon atrial septostmy. However, only two patients showed flat appearance of interatrial communication: both needed Urgent balloon atrial septostomy. The prevalence of hypermobile septum primum was significantly lower in the control group compared to patients with D-TGAIVS. Fetal echocardiographic aspects cannot predict patients with D-TGAIVS who will not need Urgent balloon atrial septostomy. Therefore, we recommended a delivery in a tertiary center, equipped for Urgent balloon atrial septostomy, for all patients with D-TGAIVS regardless of fetal echocardiographic features.

Indexed as

Transposition of Great VesselsVentricular SeptumArteriesEchocardiographyFemaleHumansHypoxiaInfant, NewbornPregnancyReproducibility of ResultsBalloon atrial septostomyFetal echocardiographyRestrictive atrial septumTransposition of the great arteries

Identifiers

PMID34052858
OpenAlexW3164209850

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.