Evidence map›Paper›PMID 34052580›Full record

Trial reportDevelopmental cognitive neuroscience2021

Neuroplasticity associated with changes in conversational turn-taking following a family-based intervention.

Rachel R Romeo, Julia A Leonard, Hannah M Grotzinger, Sydney T Robinson, Megumi E Takada, Allyson P Mackey, Ethan Scherer, Meredith L Rowe, Martin R West, John D E Gabrieli

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Developmental cognitive neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 71 citations in OpenAlex.

  1. Parents' neural dynamics in response to their children's speech.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Does early parent-driven language intervention enhance language and cognitive outcomes in preterm infants?Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  4. Article
  5. Multilingual Parents' Experiences of an Early Language and Literacy Intervention: A Qualitative Study Using the Behaviour Change Wheel.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2026
    Article
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  7. Social Determinants of Health, the developing brain, and risk and resilience for psychopathology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  8. Review
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  13. Review
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  15. Socioeconomic Status and Reading Development: Moving from "Deficit" to "Adaptation" in Neurobiological Models of Experience-Dependent Learning.Mind, brain and education : the official journal of the International Mind, Brain, and Education Society · 2023
    Article
  16. Article
  17. Language Experience during Infancy Predicts White Matter Myelination at Age 2 Years.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  18. Restricted language access during childhood affects adult brain structure in selective language regions.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Rachel R RomeoDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, United States. Electronic address: rromeo@mit.edu.
Julia A LeonardDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, United States.
Hannah M GrotzingerDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, United States.
Sydney T RobinsonDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, United States.
Megumi E TakadaDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, United States.
Allyson P MackeyDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, United States.
Ethan SchererCenter for Education Policy Research, Harvard University, United States.
Meredith L RoweGraduate School of Education, Harvard University, United States.
Martin R WestCenter for Education Policy Research, Harvard University, United States; Graduate School of Education, Harvard University, United States.
John D E GabrieliDepartment of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, United States; Center for Education Policy Research, Harvard University, United States; Integrated Learning Initiative, Massachusetts Institute of Technology, United States.
McGovern Institute for Brain Research · USHarvard University · US

Funding

Effects of linguistic input on the neural capacity for language developmentF31HD086957 · NICHD · HARVARD MEDICAL SCHOOL · PI ROMEO, RACHEL RENE · 2016 to 2017
$55k
NICHD NIH HHS F31 HD086957
6 · The paper itself

Abstract

Children's early language environments are associated with linguistic, cognitive, and academic development, as well as concurrent brain structure and function. This study investigated neurodevelopmental mechanisms linking language input to development by measuring neuroplasticity associated with an intervention designed to enhance language environments of families primarily from lower socioeconomic backgrounds. Families of 52 4-to-6 year-old children were randomly assigned to a 9-week, interactive, family-based intervention or no-contact control group. Children completed pre- and post-assessments of verbal and nonverbal cognition (n = 52), structural magnetic resonance imaging (n = 45), and home auditory recordings of language exposure (n = 39). Families who completed the intervention exhibited greater increases in adult-child conversational turns, and changes in turn-taking mediated intervention effects on language and executive functioning measures. Collapsing across groups, turn-taking changes were also positively correlated with cortical thickening in left inferior frontal and supramarginal gyri, the latter of which mediated relationships between changes in turn-taking and children's language development. This is the first study of longitudinal neuroplasticity in response to changes in children's language environments, and findings suggest that conversational turns support language development through cortical growth in language and social processing regions. This has implications for early interventions to enhance children's language environments to support neurocognitive development.

Indexed as

CommunicationNeuronal PlasticityChildChild, PreschoolHumansLanguageLanguage DevelopmentMagnetic Resonance ImagingConversational turnsFamily-Based interventionLanguage developmentLENANeuroplasticitySocioeconomic status

Identifiers

PMID34052580
PMCPMC8175277
OpenAlexW3165183385

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.