Evidence map›Paper›PMID 34052575›Full record

ArticleJournal of psychiatric research2021

Daily cannabis use in adolescents who smoke tobacco is associated with altered late-stage feedback processing: A high-density electrical mapping study.

Kristen P Morie, Jia Wu, Marc N Potenza, Suchitra Krishnan-Sarin, Linda C Mayes, Christopher J Hammond, Michael J Crowley

Open access · greenAbstract read
In one paragraph

Article in Journal of psychiatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kristen P MorieDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, 06510, USA; Child Study Center, Yale University School of Medicine, New Haven, CT, 06510, USA. Electronic address: kristen.morie@yale.edu.
Jia WuChild Study Center, Yale University School of Medicine, New Haven, CT, 06510, USA.
Marc N PotenzaDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, 06510, USA; Child Study Center, Yale University School of Medicine, New Haven, CT, 06510, USA; Connecticut Mental Health Center, New Haven, CT, 06519, USA; Connecticut Council on Problem Gambling, Wethersfield, CT, 06109, USA; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 06510, USA.
Suchitra Krishnan-SarinDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, 06510, USA; Child Study Center, Yale University School of Medicine, New Haven, CT, 06510, USA; Connecticut Mental Health Center, New Haven, CT, 06519, USA; Connecticut Council on Problem Gambling, Wethersfield, CT, 06109, USA; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 06510, USA.
Linda C MayesChild Study Center, Yale University School of Medicine, New Haven, CT, 06510, USA; Department of Pediatrics, Yale University School of Medicine, New Haven, CT, 06519, USA; Department of Psychology, Yale University School of Medicine, New Haven, CT, 06510, USA.
Christopher J HammondDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, 06510, USA; Child Study Center, Yale University School of Medicine, New Haven, CT, 06510, USA; Johns Hopkins School of Medicine, Baltimore, MD, 21218, USA.
Michael J CrowleyChild Study Center, Yale University School of Medicine, New Haven, CT, 06510, USA.
Yale University · USJohns Hopkins University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
TSF to enhance treatment of cocaine dependenceP50DA009241 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 1994 to 2018
$40.5M
TRAINING PROGRAM IN CHILDHOOD NEUROPSYCHIATRIC DISORDERST32MH018268 · NIMH · YALE UNIVERSITY · PI Michael H Bloch, MICHAEL J CROWLEY · 1985 to 2026
$11.0M
REGULATION OF AROUSAL AND ATTENTION IN COCAINE EXPOSEDR01DA006025 · NIDA · YALE UNIVERSITY · PI MAYES, LINDA CAROL · 1992 to 2007
$6.0M
Research Training Fellowship in Substance use and Addiction (RTFSA)T32DA007238 · NIDA · YALE UNIVERSITY · PI BRIAN D. KILUK, ISMENE L. PETRAKIS · 1988 to 2026
$5.7M
Interdisciplinary Research on Stress, Self-Control & AddictionUL1DE019586 · NIDCR · YALE UNIVERSITY · PI SINHA, RAJITA · 2008 to 2011
$5.0M
Neural mechanisms of CBT in cocaine dependence (Gender Differences Supplement)R01DA035058 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M., POTENZA, MARC N · 2013 to 2016
$2.3M
Cocaine-Exposed Children & Event Related Potential Studies of NeurocognitionR01DA017863 · NIDA · YALE UNIVERSITY · PI MAYES, LINDA CAROL · 2004 to 2008
$1.7M
fMRI of Stress & Self-Control in Smoking & Obesity (7 of 14)RL1AA017539 · NIAAA · YALE UNIVERSITY · PI POTENZA, MARC N · 2007 to 2011
$1.3M
Development of Reward Processing in prenatally exposed adolescents and young adultsK01DA042937 · NIDA · YALE UNIVERSITY · PI MORIE, KRISTEN PAULA · 2017 to 2021
$907k
Neural Correlates of Negative Reinforcement in Adolescence & Substance Use RiskK01DA034125 · NIDA · YALE UNIVERSITY · PI CROWLEY, MICHAEL J · 2012 to 2016
$823k
Functional networks related to cocaine dependence and its treatment and relapseR01DA039136 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2016 to 2018
$754k
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS RL1 AA017539NIDA NIH HHS K01 DA034125NIDA NIH HHS K01 DA042937NIDA NIH HHS K05 DA020091NIDA NIH HHS P50 DA009241NIDA NIH HHS R01 DA006025NIDA NIH HHS R01 DA017863NIDA NIH HHS R01 DA035058NIDA NIH HHS R01 DA039136NIDA NIH HHS R21 DA030665NIDA NIH HHS T32 DA007238NIDCR NIH HHS UL1 DE019586NIMH NIH HHS T32 MH018268
6 · The paper itself

Abstract

Impairments in feedback processing, often associated with risk-taking behavior, may have implications for development of substance abuse in adolescents. The most commonly used substances by adolescents include tobacco and cannabis, with some individuals using both substances, potentially heightening risk. Our objective was to examine feedback processing and impulsivity in adolescents who smoke cigarettes and use cannabis daily (N = 21), comparing them with adolescents who smoke cigarettes daily and use cannabis occasionally (N = 18) and non-smoking (N = 27) adolescents. To do this, the Balloon Analog Risk Task (BART) with concurrent EEG was used to measure risk-related feedback processing, and impulsivity was measured using the Barratt's impulsiveness scale (BIS-11). It was found that adolescent daily tobacco/cannabis smoking was associated with higher BIS-11 scores, shortened feedback-related-negativity (FRN) latencies and reduced P300 amplitudes. In addition, FRN latencies during win conditions were inversely associated with tobacco-use severity, indicated by scores on the Fagerstrom Test for Nicotine Dependence (FTND), and with BIS-11 scores. Adolescents with concurrent tobacco and cannabis use show altered feedback processing and higher impulsivity. Future work should disentangle whether the effect reflects risk, consequences of use or both.

Indexed as

CannabisMarijuana SmokingTobacco ProductsAdolescentFeedbackHumansAddictive behaviorsAdolescentsCannabisElectroencephalographyFeedback processingImpulsivityRisk-takingTobacco

Identifiers

PMID34052575
PMCPMC8314801
OpenAlexW3165105491

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.