Evidence map›Paper›PMID 34051865›Full record

ReviewStem cell research & therapy2021

Principles for establishment of the stem cell bank and its applications on management of sports injuries.

Bao-Shi Fan, Yang Liu, Ji-Ying Zhang, You-Rong Chen, Meng Yang, Jia-Kuo Yu

Open access · goldAbstract readReview
In one paragraph

Review in Stem cell research & therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bao-Shi Fan *Sports Medicine Department of the Institution of Peking University Third Hospital, Beijing Key Laboratory of Sports Injuries, No. 49 North Garden Road, Beijing, 100191, China.
Yang Liu *Sports Medicine Department of the Institution of Peking University Third Hospital, Beijing Key Laboratory of Sports Injuries, No. 49 North Garden Road, Beijing, 100191, China.
Ji-Ying ZhangSports Medicine Department of the Institution of Peking University Third Hospital, Beijing Key Laboratory of Sports Injuries, No. 49 North Garden Road, Beijing, 100191, China.
You-Rong ChenSports Medicine Department of the Institution of Peking University Third Hospital, Beijing Key Laboratory of Sports Injuries, No. 49 North Garden Road, Beijing, 100191, China.
Meng YangSports Medicine Department of the Institution of Peking University Third Hospital, Beijing Key Laboratory of Sports Injuries, No. 49 North Garden Road, Beijing, 100191, China.
Jia-Kuo YuSports Medicine Department of the Institution of Peking University Third Hospital, Beijing Key Laboratory of Sports Injuries, No. 49 North Garden Road, Beijing, 100191, China. yujiakuo@126.com.ORCID 0000-0001-6260-7017
Peking University · CNWeifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe stem cells of the stem cell banks have prominent problems for insufficient sources, easy contamination, unstable biological characteristics after serial subcultivations, and high cost.

methodsAfter collecting the construction processes of the existing stem cell banks and suggestions from authoritative experts in the past 10 years, 230 reference principles were obtained, and finally, the principles of "5C" for the establishment of modern standardized stem cell banks were summarized, and their related applications on the management of sports injuries were reviewed as well.

resultsThe basic principles of "5C" for the establishment of modern standardized stem cell banks include (1) principle of informed consent, (2) confidentiality principle, (3) conformity principle, (4) contamination-free principle, and (5) commonweal principle. The applications of stem cells on repairs, reconstructions, and regenerations of sports injuries were also reviewed, especially in tissue-engineered cartilage, tissue-engineered meniscus, and tissue-engineered ligament.

conclusionsThe proposal of the basic principles of "5C" is conducive to relevant stem cell researchers and clinical medical experts to build modern stem cell banks in a more standardized and efficient manner while avoiding some major mistakes or problems that may occur in the future. On this basis, stem cells from stem cell banks would be increasingly used in the management of sports injuries. More importantly, these days, getting stem cell samples are difficult in a short time, and such banks with proper legal consent may help the scientific community.

Indexed as

Athletic InjuriesHumansStem CellsBasic principleStem cellStem cell bankTissue-engineered cartilageTissue-engineered ligamentTissue-engineered meniscus

Identifiers

PMID34051865
PMCPMC8164236
OpenAlexW3164088099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.