Evidence map›Paper›PMID 34051825›Full record

ArticleJournal of medical case reports2021

Membranous nephropathy and autoimmune hepatitis in the setting of acute Helicobacter pylori infection: a case report.

Zeid Nesheiwat, Judy Daboul, Ganesh Prasad Merugu, Sreedhar Adapa, Mamtha Balla

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. AcuteInfection and drug resistance · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zeid NesheiwatDepartment of Internal Medicine, The University of Toledo College of Medicine, 2100 Central Avenue 2nd floor, Toledo, Ohio, 43606, USA. nesheiwatzeid@gmail.com.ORCID http://orcid.org/0000-0002-4975-8598
Judy DaboulDepartment of Internal Medicine, The University of Toledo College of Medicine, 2100 Central Avenue 2nd floor, Toledo, Ohio, 43606, USA.
Ganesh Prasad MeruguDivision Chief and Geriatric Medicine Fellowship Director, Division of Geriatric Medicine, Department of Family Medicine, The University of Toledo College of Medicine, 3000 Arlington Avenue, Toledo, Ohio, 43614, USA.
Sreedhar AdapaDepartment of Internal Medicine, Division of Nephrology, Adventist Medical Center, 115 Mall Drive, Hanford, CA, 93230, USA.
Mamtha BallaDepartment of Internal Medicine, The University of Toledo College of Medicine, 2100 Central Avenue 2nd floor, Toledo, Ohio, 43606, USA.
University of Toledo · USAdventist HealthCare · USProMedica Toledo Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMembranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults worldwide. A growing body of evidence indicates a pathogenic and autoimmune correlation between Helicobacter pylori infection, MN, and autoimmune liver disease. CASE PRESENTATION: A 47-year-old African American woman presented to our institution with epigastric pain and vomiting. In-patient hospital workup included a thorough abdominal evaluation including esophagogastroduodenoscopy and liver biopsy, which revealed active H. pylori infection and autoimmune hepatitis. The patient was incidentally also found to have nephrotic-range proteinuria. Renal workup including kidney biopsy established the diagnosis of MN. Proteinuria improved after initiation of triple therapy for H. pylori infection.

conclusionThis case adds to the growing evidence of a correlation between H. pylori infection, MN, and autoimmune liver disease. This report demonstrates a unique case of a patient with MN, autoimmune hepatitis (AIH)/primary biliary cholangitis (PBC), and HP who underwent triple-eradication antibiotic treatment that resulted in an ultimate resolution of all these conditions.

Indexed as

Glomerulonephritis, MembranousHelicobacter InfectionsHelicobacter pyloriHepatitis, AutoimmuneAdultFemaleHumansKidneyMiddle AgedAutoimmune diseasesCase reportHelicobacter pylori infectionHepatitisKidney biopsyMembranous nephropathyNephrotic syndromeProteinuria

Identifiers

PMID34051825
PMCPMC8164793
OpenAlexW3165488198

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.