Evidence map›Paper›PMID 34051173›Full record

ArticleAmerican journal of ophthalmology2021

Steps to Measurement Floor of an Optical Microangiography Device in Glaucoma.

Mark J Phillips, Duyen Dinh-Dang, Kyle Bolo, Bruce Burkemper, Jae C Lee, Vivian H LeTran, Brenda R Chang, Dominic J Grisafe, Zhongdi Chu, Xiao Zhou and 5 more

Open access · greenAbstract read
In one paragraph

Article in American journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Abilities of circumpapillary retinal nerve fiber layer thickness and vascular density to discriminate stages in primary open-angle glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Mark J PhillipsKeck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Duyen Dinh-DangSaint Louis University School of Medicine, St. Louis, Missouri, USA.
Kyle BoloKeck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Bruce BurkemperKeck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Jae C LeeKeck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Vivian H LeTranKeck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Brenda R ChangKeck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Dominic J GrisafeKeck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Zhongdi ChuUniversity of Washington, Seattle, Washington, USA.
Xiao ZhouUniversity of Washington, Seattle, Washington, USA.
Brian J SongKeck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Benjamin Y XuKeck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Brandon WongKeck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Ruikang K WangUniversity of Washington, Seattle, Washington, USA.
Grace M RichterKeck School of Medicine of the University of Southern California, Los Angeles, California, USA. Electronic address: grichter@usc.edu.
University of Southern California · USUniversity of Washington · USSaint Louis University · US

Funding

RESEARCH TRAINING IN GERONTOLOGYT32AG000037 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, EILEEN M CRIMMINS · 1985 to 2026
$13.2M
Ultra-wide field optical coherence tomography based angiography for imaging diabetic retinopathyR01EY028753 · NEI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2018 to 2021
$2.2M
Development and Validation of Quantitative Anterior Segment OCT-based Methods to Evaluate Patients with Primary Angle Closure DiseaseK23EY029763 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI XU, BENJAMIN Y. · 2019 to 2023
$1.1M
Defining the Relationships of Retinal Microcirculation with Glaucoma, Systemic Disease, and Ocular Anatomic Factors in African AmericansK23EY027855 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI RICHTER, GRACE MARIE · 2017 to 2021
$984k
NEI NIH HHS K23 EY027855NEI NIH HHS K23 EY029763NEI NIH HHS L30 EY027140NEI NIH HHS R01 EY028753NIA NIH HHS T32 AG000037
6 · The paper itself

Abstract

purposeTo compare dynamic ranges and steps to measurement floors of peripapillary and macular metrics from a complex signal-based optical microangiography (OMAG

designCross-sectional study.

methodsImaging of 252 eyes from 173 patients with glaucoma and 123 eyes from 92 subjects without glaucoma from a glaucoma clinic was quantified using custom and commercial software. Metrics from OCT (retinal nerve fiber layer [RNFL], ganglion cell/inner plexiform layer [GCIPL]) and OCTA (custom: peripapillary vessel area density [pVAD], macular vessel area density [mVAD], and macular vessel skeleton density [mVSD]; commercial: peripapillary perfusion density [pPD

resultsMean MD (dB) for glaucomatous eyes was -5.77 (-6.45 to -5.10). The number of eyes with mild glaucoma (MD >-6), moderate glaucoma (MD -6 to -12), and severe glaucoma (MD <-12) were 164, 50, and 38, respectively. pPD

conclusionspPD

Indexed as

GlaucomaNerve FibersAngiographyCross-Sectional StudiesHumansIntraocular PressureRetinal Ganglion CellsRetinal VesselsTomography, Optical Coherence

Identifiers

PMID34051173
PMCPMC8608690
OpenAlexW3165077785

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.