ArticleGenome biology and evolution2021
Are Geckos Special in Sex Determination? Independently Evolved Differentiated ZZ/ZW Sex Chromosomes in Carphodactylid Geckos.
Article in Genome biology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 28 citations in OpenAlex.
- Sex Determination in Sponges.Molecular reproduction and development · 2026Review
- Sexual Dimorphic Expression ofSexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation · 2025Article
- Lack of Dosage Balance and Incomplete Dosage Compensation in the ZZ/ZW Gila Monster (Heloderma suspectum) Revealed by De Novo Genome Assembly.Genome biology and evolution · 2024Article
- Heteromorphic ZZ/ZW sex chromosomes sharing gene content with mammalian XX/XY are conserved in Madagascan chameleons of the genus Furcifer.Scientific reports · 2024Article
- It's a trap?! Escape from an ancient, ancestral sex chromosome system and implication of Foxl2 as the putative primary sex-determining gene in a lizard (Anguimorpha; Shinisauridae).Evolution; international journal of organic evolution · 2024Article
- Environmental (and Random?) Sex Determination in Endangered and Invasive Phelsuma Geckos.Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation · 2024Article
- It's a Trap?! Escape from an ancient, ancestral sex chromosome system and implication ofbioRxiv : the preprint server for biology · 2023Article
- Chromosome evolution in Iberolacerta, a genus that deviates from the standard karyotype formula of Lacertidae.Genetica · 2023Article
- Robertsonian fusion triggers recombination suppression on sex chromosomes in Coleonyx geckos.Scientific reports · 2023Article
- Incomplete dosage balance and dosage compensation in the ZZ/ZW Gila monster (bioRxiv : the preprint server for biology · 2023Article
- Article
- Madagascar Leaf-Tail Geckos (Cells · 2023Article
- Article
- Diversity of reptile sex chromosome evolution revealed by cytogenetic and linked-read sequencing.Zoological research · 2022Article
- Chromosome-Level Genome Assembly Reveals Dynamic Sex Chromosomes in Neotropical Leaf-Litter Geckos (Sphaerodactylidae: Sphaerodactylus).The Journal of heredity · 2022Article
- Telomere organization and the interstitial telomeric sites involvement in insects and vertebrates chromosome evolution.Genetics and molecular biology · 2022Article
- Review
- Article
- Sex chromosome evolution among amniotes: is the origin of sex chromosomes non-random?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Do male and female heterogamety really differ in expression regulation? Lack of global dosage balance in pygopodid geckos.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amniotes possess astonishing variability in sex determination ranging from environmental sex determination (ESD) to genotypic sex determination (GSD) with highly differentiated sex chromosomes. Geckos are one of the few amniote groups with substantial variability in sex determination. What makes them special in this respect? We hypothesized that the extraordinary variability of sex determination in geckos can be explained by two alternatives: 1) unusual lability of sex determination, predicting that the current GSD systems were recently formed and are prone to turnovers; and 2) independent transitions from the ancestral ESD to later stable GSD, which assumes that geckos possessed ancestrally ESD, but once sex chromosomes emerged, they remain stable in the long term. Here, based on genomic data, we document that the differentiated ZZ/ZW sex chromosomes evolved within carphodactylid geckos independently from other gekkotan lineages and remained stable in the genera Nephrurus, Underwoodisaurus, and Saltuarius for at least 15 Myr and potentially up to 45 Myr. These results together with evidence for the stability of sex chromosomes in other gekkotan lineages support more our second hypothesis suggesting that geckos do not dramatically differ from the evolutionary transitions in sex determination observed in the majority of the amniote lineages.
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