Evidence map›Paper›PMID 34050801›Full record

ArticleEuropean radiology2021

Using prostate contrast retention (PCR) as the procedural endpoint in prostatic artery embolization for benign prostatic hyperplasia.

Antoine Hakimé, Jimmy Kyaw Tun, François Haab, Jean Luc Sarrazin, Thierry De Baere, Lambros Tselikas, Viseth Kuoch

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Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Antoine HakiméDepartment of Interventional Radiology, American Hospital of Paris, Neuilly-sur-Seine, Paris, France. thakime@yahoo.com.ORCID http://orcid.org/0000-0002-0546-9786
Jimmy Kyaw TunDepartment of Interventional Radiology, The Royal London Hospital, Barts Health NHS Trust, London, E1 1BB, UK.
François HaabDepartment of Urology, American Hospital of Paris, Neuilly-sur-Seine, Paris, France.
Jean Luc SarrazinDepartment of Interventional Radiology, American Hospital of Paris, Neuilly-sur-Seine, Paris, France.
Thierry De BaereDepartment of Surgical Radiology, Institut Gustave Roussy, Villejuif, France.
Lambros TselikasDepartment of Surgical Radiology, Institut Gustave Roussy, Villejuif, France.
Viseth KuochDepartment of Radiology, Hôpital Sud Francilien, Corbeil-Essonnes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe failure rate following prostate artery embolization (PAE) is around 20%, which may in part result from inadequate embolization. Prostate contrast retention (PCR) adequacy on immediate post-embolization cone-beam CT may provide better assessment of embolization completeness than arterial contrast stasis seen on fluoroscopy alone. The aim of this study was to evaluate outcomes of PAE using PCR adequacy as the procedural endpoint.

methodsA retrospective cohort study of all PAE cases using this technique at a single large volume center was conducted. Following initial embolization of the main prostatic arteries, if PCR was inadequate, additional embolization was performed. Technical success (adequate PCR) was defined as > 75% global prostate gland contrast staining. Clinical success was determined in accordance to CIRSE standards of practice.

resultsOne hundred sixty-five patients (mean age 68 ± 8.4 years) underwent PAE from June 2017 to March 2019. Technical and clinical success rates were 98.8% and 96.4% respectively. Clinical success rate was significantly higher in patients with adequate PCR. International Prostate Symptom Scores (IPSS) and Quality of Life (QoL) scores significantly improved at 1-, 3-, 6-, and 12-month follow-up when compared to baseline. Prostate volume (PV) and post-voiding residual bladder volume were significantly reduced at 3, 6, and 12 months in comparison to baseline. Mild (Clavien-Dindo grade I/II) and moderate (grade III) complication rates were 12.1% and 3.6% respectively.

conclusionsBy using PCR adequacy as a guide to determine the procedure endpoint for PAE, it may be possible to achieve more complete embolization and thus higher clinical success rates. KEY POINTS: • By using PCR adequacy as a guide to determine the procedure endpoint for PAE, it may be possible to achieve more complete embolization and thus higher clinical success rates.

Indexed as

Embolization, TherapeuticLower Urinary Tract SymptomsProstatic HyperplasiaAgedArteriesHumansMaleMiddle AgedQuality of LifeRetrospective StudiesTreatment OutcomeEmbolization, therapeuticProstate hyperplasiaSpiral cone-beam computed tomography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.