Evidence map›Paper›PMID 34050777›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

Katharina Dendl, Stefan A Koerber, Rebecca Finck, Kgomotso M G Mokoala, Fabian Staudinger, Lisa Schillings, Ulrike Heger, Manuel Röhrich, Clemens Kratochwil, Mike Sathekge and 4 more

Registry-linked trialOpen access · hybridAbstract readComment
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05903807 ([68Ga]Ga-FAPI-46 PET/CT), which is not on this map. Cited by 91 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 6 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05903807 phase2terminatednot on this mapstarted 2023, after this paper: background citation

[68Ga]Ga-FAPI-46 PET/CT: The Diagnostic Accuracy for Primary Staging and Re-staging of Patients With Ovarian Cancer

TypeinterventionalSponsorAalborg University HospitalRan2023 to 2026Enrolled20ConditionsOvarian CancerArms68Ga-FAPi-46
3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 6 syntheses or guidelines pooled it, 168 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Comparison ofFrontiers in oncology · 2023
    Pooled it
  4. Pooled it
  5. A systematic review of [Frontiers in oncology · 2022
    Pooled it
  6. Pooled it
  7. Non-specific uptake ofScientific reports · 2024
    Trial
  8. Comparative Evaluation of [Molecular imaging and biology · 2026
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Abnormal adnexal uptake inJournal of ovarian research · 2026
    Article
  14. Comparative evaluation of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  15. Comparative analysis ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  16. Review
  17. Article
  18. Comparison between [EJNMMI research · 2026
    Article
  19. Comparative Performance ofWorld journal of nuclear medicine · 2026
    Article
  20. Review

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Comment on
    [2023
5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Katharina DendlDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Stefan A KoerberDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany.
Rebecca FinckDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Kgomotso M G MokoalaDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Private Bag X169, Pretoria, 0001, South Africa.
Fabian StaudingerDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Lisa SchillingsDepartment of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Ulrike HegerDepartment of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.
Manuel RöhrichDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Clemens KratochwilDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Mike SathekgeDepartment of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Private Bag X169, Pretoria, 0001, South Africa.
Dirk JägerDepartment of Medical Oncology, Heidelberg University Hospital and National Center for Tumor Diseases (NCT), Heidelberg, Germany.
Jürgen DebusDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany.
Uwe HaberkornDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Frederik L GieselDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany. frederik@egiesel.com.
University Hospital Heidelberg · DEGerman Cancer Research Center · DEHeidelberg University · DENational Center for Tumor Diseases · DESteve Biko Hospital · ZAUniversity of Pretoria · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePATIENTS AND

methodsA total of 31 patients (median age 59.5) from two centers with several gynecological tumors (breast cancer; ovarian cancer; cervical cancer; endometrial cancer; leiomyosarcoma of the uterus; tubal cancer) underwent

resultsIn 8 out of 31 patients, the primary tumor was present, and all 31 patients showed lesions suspicious for metastasis (n = 81) demonstrating a high mean SUVmax in both the primary (SUVmax 11.6) and metastatic lesions (SUVmax 9.7). TBR was significantly higher in

conclusionDue to high tracer uptake resulting in sharp contrasts in primary and metastatic lesions and higher TBRs than

Indexed as

Genital Neoplasms, FemalePositron Emission Tomography Computed TomographyAdultFemaleGallium RadioisotopesHumansMiddle AgedRetrospective StudiesTissue DistributionGallium RadioisotopesFAPIFibroblast activation proteinGynecological malignanciesPETSUV

Identifiers

PMID34050777
PMCPMC8484099
OpenAlexW3164206095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.