Evidence map›Paper›PMID 34050646›Full record

ArticleInternational journal of epidemiology2021

No causal associations between childhood family income and subsequent psychiatric disorders, substance misuse and violent crime arrests: a nationwide Finnish study of >650 000 individuals and their siblings.

Amir Sariaslan, Janne Mikkonen, Mikko Aaltonen, Heikki Hiilamo, Pekka Martikainen, Seena Fazel

Open access · hybridAbstract read
In one paragraph

Article in International journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
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  5. Parental income and psychiatric disorders from age 10 to 40: a genetically informative population study.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Article
  6. Article
  7. Childhood family income and medication use in youth.Journal of epidemiology and community health · 2025
    Article
  8. Article
  9. Article
  10. Neighborhood selection by parent personality, depression, and coparent support: A two-study replication.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2024
    Article
  11. Article
  12. The social determinants of mental health and disorder: evidence, prevention and recommendations.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Amir SariaslanSocial and Public Policy Unit, Faculty of Social Sciences, University of Helsinki, Helsinki, Finland.ORCID 0000-0002-6151-3278
Janne MikkonenPopulation Research Unit, Faculty of Social Sciences, University of Helsinki, Helsinki, Finland.
Mikko AaltonenUEF Law School, University of Eastern Finland, Joensuu, Finland.
Heikki HiilamoSocial and Public Policy Unit, Faculty of Social Sciences, University of Helsinki, Helsinki, Finland.
Pekka MartikainenPopulation Research Unit, Faculty of Social Sciences, University of Helsinki, Helsinki, Finland.ORCID 0000-0001-9374-1438
Seena FazelDepartment of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK.
University of Helsinki · FIUniversity of Eastern Finland · FIWarneford Hospital · GB

Funding

Wellcome TrustWellcome Trust 202836/Z/16/Z
6 · The paper itself

Abstract

backgroundChildhood family income has been shown to be associated with later psychiatric disorders, substance misuse and violent crime, but the consistency, strength and causal nature of these associations remain unclear.

methodsWe conducted a nationwide cohort and co-sibling study of 650 680 individuals (426 886 siblings) born in Finland between 1986 and 1996 to re-examine these associations by accounting for unmeasured confounders shared between siblings. The participants were followed up from their 15th birthday until they either migrated, died, met criteria for the outcome of interest or reached the end of the study period (31 December 2017 or 31 December 2018 for substance misuse). The associations were adjusted for sex, birth year and birth order, and expressed as adjusted hazard ratios (aHRs). The outcomes included a diagnosis of a severe mental illness (schizophrenia-spectrum disorders or bipolar disorder), depression and anxiety. Substance misuse (e.g. medication prescription, hospitalization or death due to a substance use disorder or arrest for drug-related crime) and violent crime arrests were also examined. Stratified Cox regression models accounted for unmeasured confounders shared between differentially exposed siblings.

resultsFor each $15 000 increase in family income at age 15 years, the risks of the outcomes were reduced by between 9% in severe mental illness (aHR = 0.91; 95% confidence interval: 0.90-0.92) and 23% in violent crime arrests (aHR = 0.77; 0.76-0.78). These associations were fully attenuated in the sibling-comparison models (aHR range: 0.99-1.00). Sensitivity analyses confirmed the latter findings.

conclusionsAssociations between childhood family income and subsequent risks for psychiatric disorders, substance misuse and violent crime arrest were not consistent with a causal interpretation.

Indexed as

Mental DisordersSubstance-Related DisordersAdolescentChildCrimeFinlandHumansRegistriesRisk FactorsSiblingsSwedenanxietybipolar disorderdepressionfamily incomepublic healthquasi-experimental research designsschizophreniaSocio-economic statussubstance-use disordersviolence

Identifiers

PMID34050646
PMCPMC8580272
OpenAlexW3164920940

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.