Evidence map›Paper›PMID 34050456›Full record

ArticleBiological trace element research2022

Effect of Different Garlic Preparations on Testosterone, Thyroid Hormones, and Some Serum Trace Elements in Rats.

Aliaa Ezz El Arab, Osama Ahmed Abbas, Mohamad Taha Abdelrahman

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Aliaa Ezz El ArabRadioisotopes Department, Egyptian Atomic Energy Authority, Giza, Egypt.
Osama Ahmed AbbasRadioisotopes Department, Egyptian Atomic Energy Authority, Giza, Egypt.
Mohamad Taha AbdelrahmanRadioisotopes Department, Egyptian Atomic Energy Authority, Giza, Egypt. mohamadt.abdelrahman@gmail.com.ORCID http://orcid.org/0000-0003-0723-8698
Egyptian Atomic Energy Authority · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Garlic is a house-available vegetable which is widely used for its spicy and medicinal benefits. Impact of different preparations on testosterone, thyroid hormones, and blood micro and trace elements were studied. Eight groups of male albino rats were selected including control group and other seven groups administered different doses of different garlic preparations by oral gavages for 1 month. At the end of the experiment, blood samples were collected for determination of serum hormones by radioimmunoassay, serum micro and trace elements by inductively coupled plasma-optical emission spectrometry (ICP-OES), and testes tissues for histological examination. All treated groups with different garlic preparations revealed a highly significant decrease of testosterone level in rats as compared to control which confirmed with histological changes. Increase of thyroid hormones in some groups was seen. Hypokalemia and hypernatremia effect was recorded due to garlic treatments. Calcium, magnesium, selenium, zinc, manganese, iron, cadmium, lead, silicon, molybdenum, germanium, barium, boron, niobium, and aluminum levels showed alterations in different preparations groups. On the other hand, insignificant changes of strontium, chromium, cesium, and the nickel serum levels were noted. Interestingly, although all garlic preparations have negative effects on serum testosterone level and testicular tissues, some garlic preparations have different effects on blood elements. Consequently, it infers that the usage of different garlic preparations must abide benefit/risk assessment to avoid unexpected health issues.

Indexed as

GarlicTrace ElementsAluminumAnimalsCopperMaleRatsTestosteroneThyroid HormonesAluminumCopperTestosteroneThyroid HormonesTrace ElementsBlood micro elementsGarlicThyroid hormonesTrace elements

Identifiers

PMID34050456
OpenAlexW3164552421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.