Evidence map›Paper›PMID 34050422›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022

Impulsivity traits and awareness of motor intention in Parkinson's disease: a proof-of-concept study.

Fabio Giovannelli, Chiara Menichetti, Lorenzo Kiferle, Laura Maria Raglione, Stefania Brotini, Paola Vanni, Duccio Bacci, Mariella Baldini, Alessandra Borgheresi, Alessandra Del Bene and 7 more

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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Fabio GiovannelliSection of Psychology - Department of Neuroscience, Psychology, Drug Research and Child's Health (NEUROFARBA), University of Florence, Florence, Italy.
Chiara MenichettiUnit of Neurology of Pistoia, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Lorenzo KiferleUnit of Neurology of Prato, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Laura Maria RaglioneUnit of Neurology of Florence, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Stefania BrotiniUnit of Neurology of Empoli, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Paola VanniUnit of Neurology of Florence-OSMA, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Duccio BacciUnit of Neurology of Florence-OSMA, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Mariella BaldiniUnit of Neurology of Empoli, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Alessandra BorgheresiUnit of Neurology of Florence, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Alessandra Del BeneUnit of Neurology of Pistoia, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Enrico GrassiUnit of Neurology of Prato, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Leonello GuidiUnit of Neurology of Empoli, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Lucia ToscaniUnit of Neurology of Florence-OSMA, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Gino VolpiUnit of Neurology of Pistoia, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Pasquale PalumboUnit of Neurology of Prato, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy.
Maria Pia ViggianoSection of Psychology - Department of Neuroscience, Psychology, Drug Research and Child's Health (NEUROFARBA), University of Florence, Florence, Italy.
Massimo CincottaUnit of Neurology of Florence, Cerebrovascular and Neurodegenerative Disease Area of the Department of Medical Specialties, Central Tuscany Local Health Authority, Florence, Italy. massimo.cincotta@uslcentro.toscana.it.ORCID http://orcid.org/0000-0001-5223-646X
Agenzia Regionale di Sanità della Toscana · ITUniversity of Florence · IT

Funding

Ente Cassa di Risparmio di Firenze AUT. 462/2016
6 · The paper itself

Abstract

introductionIn patients with Parkinson's disease (PD), impulsivity is still a matter of investigation. It has been hypothesized that impulsive personality traits may favour impulse control disorder (ICD) onset during dopaminergic therapy. In healthy subjects, a relationship between the awareness of motor intention and impulsive personality traits assessed by the Barratt impulsivity scale (BIS-11) has been reported. The aim of this study was to evaluate the relationship between the awareness of voluntary action and impulsivity traits in PD.

methodsTwenty-eight PD patients (stages I-III on the Hoehn and Yahr scale) underwent an impulsivity trait assessment by the BIS-11 scale and a task based on the Libet's clock. Participants were requested to perform a self-initiated movement and report the time they first feel their intention to move (W-judgement) or the time of the actual movement (M-judgement).

resultsIn patients with higher BIS-11 scores, the time lag between the W-judgement and the actual movement was significantly lower than in patients with lower BIS-11. No difference emerged in the M-judgement.

conclusionData suggest that also in PD patients, the impulsive personality trait is related to a "delayed" awareness of motor intention and therefore to a shorter interval to allow a conscious "veto" of the impending action. Characterization of the temporal profile of awareness of motor intention could prove useful in identifying PD patients at risk of developing ICDs during dopaminergic treatment.

Indexed as

Parkinson DiseaseHumansImpulsive BehaviorIntentionJudgmentMovementImpulse disordersImpulsivityLibet’s clockMotor awarenessParkinson’s disease

Identifiers

PMID34050422
OpenAlexW3164938183

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.