Evidence map›Paper›PMID 34050386›Full record

ArticleEuropean radiology2021

Evaluating a calcium-aware kernel for CT CAC scoring with varying surrounding materials and heart rates: a dynamic phantom study.

Niels R van der Werf, Ronald Booij, Bernhard Schmidt, Thomas G Flohr, Tim Leiner, Joël J de Groen, Daniël Bos, Ricardo P J Budde, Martin J Willemink, Marcel J W Greuter

Open access · hybridAbstract read
In one paragraph

Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Niels R van der WerfDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands. n.vanderwerf@erasmusmc.nl.ORCID http://orcid.org/0000-0003-0138-052X
Ronald BooijDepartment of Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Bernhard SchmidtComputed Tomography, Siemens Healthineers, Forchheim, Germany.
Thomas G FlohrComputed Tomography, Siemens Healthineers, Forchheim, Germany.
Tim LeinerDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Joël J de GroenDepartment of Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Daniël BosDepartment of Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Ricardo P J BuddeDepartment of Radiology & Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Martin J WilleminkDepartment of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Marcel J W GreuterDepartment of Radiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Erasmus MC · NLSiemens Healthineers (Germany) · DEStanford University · USUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe purpose of this study was twofold. First, the influence of a novel calcium-aware (Ca-aware) computed tomography (CT) reconstruction technique on coronary artery calcium (CAC) scores surrounded by a variety of tissues was assessed. Second, the performance of the Ca-aware reconstruction technique on moving CAC was evaluated with a dynamic phantom.

methodsAn artificial coronary artery, containing two CAC of equal size and different densities (196 ± 3, 380 ± 2 mg hydroxyapatite cm

resultsFor all heart rates, Agatston scores for CAC submerged in fat were comparable to the reference, for the reduced-kVp acquisition with Ca-aware reconstruction kernel. For water and soft tissue, medium-density Agatston scores were again comparable to the reference for all heart rates. Low-density Agatston scores showed relevant deviations, up to 15% and 23% for water and soft tissue, respectively.

conclusionCT CAC scoring with varying surrounding materials and heart rates is feasible at patient-specific tube voltages with the novel Ca-aware reconstruction technique. KEY POINTS: • A dedicated calcium-aware reconstruction kernel results in similar Agatston scores for CAC surrounded by fatty materials regardless of CAC density and heart rate. • Application of a dedicated calcium-aware reconstruction kernel allows for radiation dose reduction. • Mass scores determined with CT underestimated physical mass.

Indexed as

CalciumCoronary Artery DiseaseCoronary AngiographyHeart RateHumansPhantoms, ImagingRadiation DosageReproducibility of ResultsTomography, X-Ray ComputedCalciumCoronary artery diseaseDiagnostic imagingRadiation dosageTomography, x-ray computed

Identifiers

PMID34050386
PMCPMC8589753
OpenAlexW3164774398

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.