ReviewNature reviews. Cardiology2021
Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension.
Review in Nature reviews. Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 841 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Addressing Gaps in the Hypertension and Diabetes Care Continuum in Rural Bangladesh Through mHealth and Decentralized Primary Care: The Dinajpur Study
A Single Centre Randomised Prospective Cross-over Study to Assess Agreement Between Blood Pressure Measurements Taken Using Cuffless Wearable and Cuffed, Ambulatory Blood Pressure Monitoring Devices.
The Combined Effect of the Mediterranean Diet and Intermittent Fasting on Hypertension
Examination of the Dose-dependent Effects of Isometric Resistance Training on Decreases in Blood Pressure in Pre- and Hypertensive Adults
Who cites it
841 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- When Methods Matter: An Umbrella Review of Lorundrostat and the Impact of Analytical Decisions on Reported Blood Pressure and Safety Outcomes.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026Pooled it
- Global prevalence of nocturnal hypertension: systematic review and meta-analysis.BMC public health · 2026Pooled it
- Accelerated epigenetic age in hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Pooled it
- Effects of Nicotinamide Mononucleotide Supplementation on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Nutrients · 2026Pooled it
- Prevalence of hypertension among adults in Nigeria: a systematic review and meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- The Association Between Sleep Duration and the Risk of Hypertension: A Systematic Review and Meta-analysis of Cohort Studies.Journal of general internal medicine · 2025Pooled it
- A series of N-of-1 dietary intervention studies with whole-grain foods and nuts reveals individual predictors of blood pressure and heart rate.European journal of clinical nutrition · 2026Trial
- Efficacy and safety of intensive antihypertensive strategy in patients with low diastolic blood pressure: a secondary analysis of a cluster randomised trial.Heart (British Cardiac Society) · 2026Trial
- Effects of a 4-Week Multi-Exercise Isometric Resistance Training Programme on Resting and Ambulatory Blood Pressure in Normotensive Adults.European journal of sport science · 2026Trial
- Systolic blood pressure time-in-target range and kidney outcomes in patients with hypertension: Findings from the STEP trial.Chinese medical journal · 2026Trial
- Clinical Decision Support System, Antihypertensive Treatment Intensification, and Blood Pressure Control: A Post Hoc Secondary Analysis of a Cluster Randomized Trial.JAMA network open · 2026Trial
- Efficacy and safety of a modified ozone-mediated neurolysis in treatment for patients with resistant hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Trial
- Chronic plateau exposure attenuates antihypertensive efficacy in highlanders: insights from the OMAN trial.Journal of hypertension · 2026Trial
- Evening home pulse pressure predicted cardiovascular events and mortality in older adults with hypertension: findings based on the STEP trial.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Trial
- SGLT2 inhibitor ameliorates hypertension by regulating the CYP4A/20-HETE pathway in the kidney.Bioscience reports · 2026Article
- Disparities in Blood Pressure Measurement.Current hypertension reports · 2026Review
- Metabolic syndrome severity and the effects of intensive blood pressure lowering: Results from the STEP randomized trial.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Sex Differences in Sleep Duration and Quality: Implications for Hypertension Risk.Current hypertension reports · 2026Review
- Sex-specific differences in the anatomical localization and severity of coronary artery disease: differential impact of conventional cardiovascular risk factors.Clinics (Sao Paulo, Brazil) · 2026Article
- Irritable Bowel Syndrome and Incident Hypertension: Epidemiologic and Genetic Insights.Biomedicines · 2026Article
781 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
High blood pressure is one of the most important risk factors for ischaemic heart disease, stroke, other cardiovascular diseases, chronic kidney disease and dementia. Mean blood pressure and the prevalence of raised blood pressure have declined substantially in high-income regions since at least the 1970s. By contrast, blood pressure has risen in East, South and Southeast Asia, Oceania and sub-Saharan Africa. Given these trends, the prevalence of hypertension is now higher in low-income and middle-income countries than in high-income countries. In 2015, an estimated 8.5 million deaths were attributable to systolic blood pressure >115 mmHg, 88% of which were in low-income and middle-income countries. Measures such as increasing the availability and affordability of fresh fruits and vegetables, lowering the sodium content of packaged and prepared food and staples such as bread, and improving the availability of dietary salt substitutes can help lower blood pressure in the entire population. The use and effectiveness of hypertension treatment vary substantially across countries. Factors influencing this variation include a country's financial resources, the extent of health insurance and health facilities, how frequently people interact with physicians and non-physician health personnel, whether a clear and widely adopted clinical guideline exists and the availability of medicines. Scaling up treatment coverage and improving its community effectiveness can substantially reduce the health burden of hypertension.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.