Evidence map›Paper›PMID 34050228›Full record

ArticleScientific reports2021

Hydrogel with silver nanoparticles synthesized by Mimosa tenuiflora for second-degree burns treatment.

Aaron Martínez-Higuera, César Rodríguez-Beas, Jesús Mauro Adolfo Villalobos-Noriega, Abraham Arizmendi-Grijalva, Carlos Ochoa-Sánchez, Eduardo Larios-Rodríguez, Juan Manuel Martínez-Soto, Ericka Rodríguez-León, Cristina Ibarra-Zazueta, Roberto Mora-Monroy and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 58 citations in OpenAlex.

  1. Differentiation ofACS omega · 2026
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  14. Plasma-Activated Hydrogels for Microbial Disinfection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  15. Review
  16. PluronicGels (Basel, Switzerland) · 2023
    Article
  17. Article
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  19. Multidrug-Resistant Pathogens in Burn Wound, Prevention, Diagnosis, and Therapeutic Approaches (Conventional Antimicrobials and Nanoparticles).The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Aaron Martínez-HigueraDepartment of Physics, Nanotechnology Graduate Program, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
César Rodríguez-BeasDepartment of Physics, Nanotechnology Graduate Program, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Jesús Mauro Adolfo Villalobos-NoriegaDepartment of Physics, Nanotechnology Graduate Program, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Abraham Arizmendi-GrijalvaDepartment of Physics, Nanotechnology Graduate Program, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Carlos Ochoa-SánchezDepartment of Physics, Nanotechnology Graduate Program, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Eduardo Larios-RodríguezDepartment of Chemical and Metallurgical Engineering, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Juan Manuel Martínez-SotoDepartment of Medicine and Health Science, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Ericka Rodríguez-LeónDepartment of Physics, Nanotechnology Graduate Program, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Cristina Ibarra-ZazuetaDepartment of Agriculture and Livestock, University of Sonora, Road to Kino Bay km 20.5, Hermosillo, Sonora, Mexico.
Roberto Mora-MonroyDepartment of Physic Researching, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Hugo Alejandro Borbón-NuñezCONACYT-Centro de Nanociencias Y Nanotecnología, UNAM, Km 107 Carretera Tijuana-Ensenada s/n, 22800, Ensenada, B.C. C.P, Mexico.
Alfonso García-GalazFood Science Coordination, Research Center in Food & Development (CIAD), Road Gustavo Enrique Astiazarán Rosas, No. 46, Col. La Victoria, 83304, Hermosillo, Sonora, Mexico.
María Del Carmen Candia-PlataDepartment of Medicine and Health Science, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Luis Fernando López-SotoDepartment of Medicine and Health Science, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Ramón Iñiguez-PalomaresDepartment of Physics, Nanotechnology Graduate Program, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico. ramon.iniguez@unison.mx.
Universidad de Sonora · MXConsejo Nacional de Humanidades, Ciencias y Tecnologías · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work we use Mimosa tenuiflora (MtE) extracts as reducing agents to synthesize silver nanoparticles (AgMt NPs) which were characterized by DPPH and Total Polyphenols Assays, UV-visible, X-ray diffractometer (XRD), high-resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS) and Thermogravimetric analysis (TGA). AgMt NPs possess average sizes of 21 nm and fcc crystalline structure, it was also confirmed that the MtE is present in the AgMt NPs even after the cleaning protocol applied. Subsequently, carbopol hydrogels were made and the MtE and the synthesized AgMt NPs were dispersed in different gels (MtE-G and AgMt NPs-G, respectively) at 100 µg/g concentration. The gels were characterized by UV-Vis, IR, and rheology. Antimicrobial tests were performed using Staphylococcus aureus and Escherichia coli. Burn wound healing was evaluated in a second-degree burn injury on a Wistar rats model for 14 days and additional skin biopsies were examined with histopathological analysis. Gel with commercial silver nanoparticles (Ag NPs) was prepared and employed as a control on the biological assays. Hydrogel system containing silver nanoparticles synthesized with Mimosa tenuiflora (AgMt NPs-G) is a promising therapeutic strategy for burn wound healing, this due to bactericidal and anti-inflammatory effects, which promotes a more effective recovery (in percentage terms) by damaged area.

Indexed as

AnimalsBurnsDrug Evaluation, PreclinicalHydrogelsMaleMetal NanoparticlesMimosaPhytotherapyPlant BarkPlant ExtractsRatsRats, WistarSilverWound HealingHydrogelsPlant ExtractsSilver

Identifiers

PMID34050228
PMCPMC8163746
OpenAlexW3164544399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.