Evidence map›Paper›PMID 34050041›Full record

Trial reportBiomedical physics & engineering express2021

Patient specific, imaging-informed modeling of rhenium-186 nanoliposome delivery via convection-enhanced delivery in glioblastoma multiforme.

Ryan T Woodall, David A Hormuth Ii, Chengyue Wu, Michael R A Abdelmalik, William T Phillips, Ande Bao, Thomas J R Hughes, Andrew J Brenner, Thomas E Yankeelov

Abstract readClinical Trial, Phase IClinical Trial, Phase II
In one paragraph

Trial report in Biomedical physics & engineering express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Image-guided subject-specific modeling of glymphatic transport and amyloid deposition.Computer methods in applied mechanics and engineering · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ryan T WoodallBiomedical Engineering, The University of Texas at Austin, Austin, Texas, United States of America.
David A Hormuth IiOden Institute for Computational Engineering and Sciences,The University of Texas at Austin, Austin, Texas, United States of America.ORCID 0000-0002-9643-1694
Chengyue WuOden Institute for Computational Engineering and Sciences,The University of Texas at Austin, Austin, Texas, United States of America.ORCID 0000-0002-3789-404X
Michael R A AbdelmalikOden Institute for Computational Engineering and Sciences,The University of Texas at Austin, Austin, Texas, United States of America.
William T PhillipsDepartments of Radiology at UT Health San Antonio, San Antonio, Texas, United States of America.
Ande BaoDepartment of Radiation Oncology, Seidman Cancer Center, University Hospitals, Cleveland Medical Center, Cleveland, Ohio, United States of America.
Thomas J R HughesOden Institute for Computational Engineering and Sciences,The University of Texas at Austin, Austin, Texas, United States of America.
Andrew J BrennerMays Cancer Center at UT Health San Antonio, San Antonio, Texas, United States of America.
Thomas E YankeelovBiomedical Engineering, The University of Texas at Austin, Austin, Texas, United States of America.ORCID 0000-0002-7022-0565

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
Quantitative Multiscale Imaging to Optimize Cancer Treatment StrategiesR01CA186193 · NCI · VANDERBILT UNIVERSITY · PI QUARANTA, VITO, RERICHA, ERIN C · 2014 to 2019
$3.1M
Clinical Development of Rhenium Nanoliposomes (RNL186) for GlioblastomaR01CA235800 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI BRENNER, ANDREW JACOB · 2019 to 2023
$3.0M
Comprehensive Training Program in Imaging Science and InformaticsT32EB007507 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI MARKEY, MIA K, RYLANDER, HENRY GRADY · 2009 to 2024
$2.7M
Image Driven Multi-Scale Modeling to Predict Treatment Response in Breast CancerU01CA174706 · NCI · VANDERBILT UNIVERSITY · PI QUARANTA, VITO, YANKEELOV, THOMAS E · 2013 to 2018
$2.5M
Using label-free Raman microscopy to predict therapeutic resistance of TNBC cellsU01CA253540 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI BROCK, AMY, YANKEELOV, THOMAS E · 2020 to 2024
$2.1M
NCI NIH HHS P30 CA016086NCI NIH HHS R01 CA186193NCI NIH HHS R01 CA235800NCI NIH HHS U01 CA174706NCI NIH HHS U01 CA253540NIBIB NIH HHS T32 EB007507
6 · The paper itself

Abstract

Convection-enhanced delivery of rhenium-186 (

Indexed as

Brain NeoplasmsGlioblastomaConvectionHumansNeoplasm Recurrence, LocalRadioisotopesRheniumRadioisotopesRheniumRhenium-186computational fluid dynamicscomputational oncologyconvection-enhanced deliveryglioblastoma multiformeradiation therapy

Identifiers

PMID34050041
PMCPMC9332136

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.