ArticleProceedings of the National Academy of Sciences of the United States of America2021
Distinct contribution of cone photoreceptor subtypes to the mammalian biological clock.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 34 citations in OpenAlex.
- Considerations and guidelines for photic measurement in field studies of the physiological effects of light.Npj biological timing and sleep · 2026Review
- Article
- Lack of strong evidence for cone photoreceptors' contribution to human melatonin suppression and alerting response to light.iScience · 2025Article
- Visible Exocytosis of the Non-Photic Signal Neuropeptide Y to the Suprachiasmatic Nucleus in Fasted Transgenic Mice Throughout Their Circadian Rhythms.Bioengineering (Basel, Switzerland) · 2025Article
- Relative importance of intensity and spectrum of artificial light at night in disrupting behavior of a nocturnal rodent.The Journal of experimental biology · 2024Article
- Timing Matters: Time of Day Impacts the Ergogenic Effects of Caffeine-A Narrative Review.Nutrients · 2024Review
- Photoperiod Induces the Epigenetic Change of theInternational journal of molecular sciences · 2023Article
- Immediate responses to ambient lightiScience · 2023Article
- Melanopsin-mediated optical entrainment regulates circadian rhythms in vertebrates.Communications biology · 2023Review
- S-Cone Photoreceptors Regulate Daily Rhythms and Light-Induced Arousal/Wakefulness in Diurnal Grass Rats (Journal of biological rhythms · 2023Article
- Tangled up in blue: Contribution of short-wavelength sensitive cones in human circadian photoentrainment.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Long wavelength light reduces the negative consequences of dim light at night.Neurobiology of disease · 2023Article
- Sleep and Circadian Rhythm Dysfunction in Animal Models of Huntington's Disease.Journal of Huntington's disease · 2023Review
- A real-time measurement system for gene expression rhythms from deep tissues of freely moving mice under light-dark conditions.Biochemistry and biophysics reports · 2022Article
- Neuronal Bmal1 regulates retinal angiogenesis and neovascularization in mice.Communications biology · 2022Article
- Adenosine, caffeine, and sleep-wake regulation: state of the science and perspectives.Journal of sleep research · 2022Review
- Spectrophotometric properties of commercially available blue blockers across multiple lighting conditions.Chronobiology international · 2022Article
- Sleep Deprivation Does not Change the Flash Electroretinogram in Wild-type andJournal of biological rhythms · 2022Article
- The photobiology of the human circadian clock.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Duration invariance and intensity dependence of the human circadian system phase shifting response to brief light flashes.Proceedings. Biological sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Ambient light detection is important for the synchronization of the circadian clock to the external solar cycle. Light signals are sent to the suprachiasmatic nuclei (SCN), the site of the major circadian pacemaker. It has been assumed that cone photoreceptors contribute minimally to synchronization. Here, however, we find that cone photoreceptors are sufficient for mediating entrainment and transmitting photic information to the SCN, as evaluated in mice that have only cones as functional photoreceptors. Using in vivo electrophysiological recordings in the SCN of freely moving cone-only mice, we observed light responses in SCN neuronal activity in response to 60-s pulses of both ultraviolet (UV) (λ
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.