Evidence map›Paper›PMID 34050014›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

What we know about effective public engagement on CRISPR and beyond.

Dietram A Scheufele, Nicole M Krause, Isabelle Freiling, Dominique Brossard

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Ethics of Human Embryo Editing via CRISPR-Cas9 Technology: A Systematic Review of Ethical Arguments, Reasons, and Concerns.HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
  5. How Gene Therapy Research Has Evolved and the Future of Oversight.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2026
    Article
  6. Article
  7. An agenda for science communication research and practice.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Our changing information ecosystem for science and why it matters for effective science communication.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Questions and Consequences of Omics in Genetically Engineered Crop Regulation.Plant-environment interactions (Hoboken, N.J.) · 2025
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dietram A ScheufeleDepartment of Life Sciences Communication, University of Wisconsin-Madison, Madison, WI 53706; scheufele@gmail.com.ORCID 0000-0002-9914-5407
Nicole M KrauseDepartment of Life Sciences Communication, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0003-0550-9546
Isabelle FreilingDepartment of Communication, University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-6046-4005
Dominique BrossardDepartment of Life Sciences Communication, University of Wisconsin-Madison, Madison, WI 53706.ORCID 0000-0002-9188-8388

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in gene editing technologies for human, plant, and animal applications have led to calls from bench and social scientists, as well as a wide variety of societal stakeholders, for broad public engagement in the decision-making about these new technologies. Unfortunately, there is limited understanding among the groups calling for public engagement on CRISPR and other emerging technologies about 1) the goals of this engagement, 2) the modes of engagement and what we know from systematic social scientific evaluations about their effectiveness, and 3) how to connect the products of these engagement exercises to societal decision or policy making. Addressing all three areas, we systematize common goals, principles, and modalities of public engagement. We evaluate empirically the likely successes of various modalities. Finally, we outline three pathways forward that deserve close attention from the scientific community as we navigate the world of Life 2.0.

Indexed as

Biomedical ResearchClustered Regularly Interspaced Short Palindromic RepeatsGene EditingPolicy MakingHumansdeliberationpolitical communicationpublic engagementpublic participationscience communication

Identifiers

PMID34050014
PMCPMC8179128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.