Evidence map›Paper›PMID 34049998›Full record

ArticleRMD open2021

CT-like images of the sacroiliac joint generated from MRI using susceptibility-weighted imaging (SWI) in patients with axial spondyloarthritis.

Dominik Deppe, Kay-Geert Hermann, Fabian Proft, Denis Poddubnyy, Felix Radny, Mikhail Protopopov, Marcus R Makowski, Torsten Diekhoff

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 54 citations in OpenAlex.

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  12. New Bone Formation in Axial Spondyloarthritis: A Review.RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Dominik DeppeDepartment of Radiology, Freie Universität Berlin, Berlin, Germany.
Kay-Geert HermannDepartment of Radiology, Freie Universität Berlin, Berlin, Germany.
Fabian ProftDepartment of Gastroenterology, Infectiology and Rheumatology, Charite Universitatsmedizin Berlin Campus Benjamin Franklin, Berlin, Germany.ORCID 0000-0003-4306-033X
Denis PoddubnyyDivision of Gastroenterology, Infectious Diseases and Rheumatology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Felix RadnyDepartment of Radiology, Freie Universität Berlin, Berlin, Germany.
Mikhail ProtopopovDepartment of Gastroenterology, Infectiology and Rheumatology, Charite Universitatsmedizin Berlin Campus Benjamin Franklin, Berlin, Germany.ORCID 0000-0003-4840-5069
Marcus R MakowskiDepartment of Radiology, Charité Universitätsmedizin Berlin, Berlin, Germany.
Torsten DiekhoffDepartment of Radiology, Freie Universität Berlin, Berlin, Germany torsten.diekhoff@charite.de.ORCID 0000-0003-3593-1449
Charité - Universitätsmedizin Berlin · DEFreie Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo analyse the added value of susceptibility-weighted imaging (SWI) compared with standard T1-weighted (T1) MRI for detecting structural lesions of the sacroiliac joint (SIJ) in patients with axial spondyloarthritis (axSpA) using CT as reference standard. MATERIAL AND

methodsSixty-eight patients with suspected or proven axSpA underwent both MRI and CT of the SIJ on the same day. Two readers separately scored CT, T1 and SWI for the presence of erosions, sclerosis and joint space changes using an established 24-region SIJ model. Disagreement was resolved by a third reader. Diagnostic accuracy (McNemar test), Cohen's kappa (k), sensitivity (SE) and specificity were calculated on the joint level using CT as reference.

resultsIn CT, 38 joints showed erosions, 67 sclerosis and 37 joint space changes. Agreement with CT for erosions was 92.6% (k=0.811 (0.7-0.92)) in SWI and 87.5% (k=0.682 (0.54-0.82)) in T1 (p=0.143) and agreement for sclerosis 84.6% (k=0.69 (0.57-0.81)) and 62.5% (k=0.241 (0.13-0.35)) (p<0.001), respectively. This resulted in superior SE of SWI (81.6% vs 73.7%) for erosions and sclerosis (74.6% vs 23.9%) at a minor expense of SP. No differences were detected for joint space changes.

conclusionIn patients with axSpA, SWI depicts erosions and sclerosis more accurately than T1 spin echo MRI at 1.5 T.

Indexed as

Sacroiliac JointSpondylarthritisHumansMagnetic Resonance ImagingSensitivity and SpecificityTomography, X-Ray ComputedankylosingarthritisMRIspondylitis

Identifiers

PMID34049998
PMCPMC8166621
OpenAlexW3164363894

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.