Evidence map›Paper›PMID 34049996›Full record

ArticleNeurology(R) neuroimmunology & neuroinflammation2021

Aggressive Herpes Zoster in Young Patients With Multiple Sclerosis Under Dimethyl Fumarate: Significance of CD8

Maria C Anagnostouli, Georgios Velonakis, Marinos C Dalakas

Abstract readCase Reports
In one paragraph

Article in Neurology(R) neuroimmunology & neuroinflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Acute retinal necrosis associated with dimethyl fumarate.Multiple sclerosis (Houndmills, Basingstoke, England) · 2025
    Article
  2. Ten Years ofNeurology(R) neuroimmunology & neuroinflammation · 2025
    Article
  3. Reemerging Infectious Diseases and Neuroimmunologic Complications.Neurology(R) neuroimmunology & neuroinflammation · 2025
    Review
  4. Article
  5. Article
  6. Fingolimod as a first- or second-line treatment in a mini-series of young Hellenic patients with adolescent-onset multiple sclerosis: focus on immunological data.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maria C AnagnostouliFrom the Multiple Sclerosis and Demyelinating Diseases Unit and Immunogenetics Laboratory (M.C.A.), 1st Department of Neurology, Medical School, National and Kapodistrian University of Athens, NKUA, Aeginition University Hospital, Athens, Greece; Research Unit of Radiology (G.V.), 2nd Department of Radiology, Medical School, National and Kapodistrian University of Athens, Greece; Neuroimmunology Unit (M.C.D.), Department of Pathophysiology, National and Kapodistrian University of Athens, Greece; and Department of Neurology (M.C.D.), Thomas Jefferson University, Philadelphia, PA. managnost@med.uoa.gr.
Georgios VelonakisFrom the Multiple Sclerosis and Demyelinating Diseases Unit and Immunogenetics Laboratory (M.C.A.), 1st Department of Neurology, Medical School, National and Kapodistrian University of Athens, NKUA, Aeginition University Hospital, Athens, Greece; Research Unit of Radiology (G.V.), 2nd Department of Radiology, Medical School, National and Kapodistrian University of Athens, Greece; Neuroimmunology Unit (M.C.D.), Department of Pathophysiology, National and Kapodistrian University of Athens, Greece; and Department of Neurology (M.C.D.), Thomas Jefferson University, Philadelphia, PA.ORCID 0000-0002-0050-284X
Marinos C DalakasFrom the Multiple Sclerosis and Demyelinating Diseases Unit and Immunogenetics Laboratory (M.C.A.), 1st Department of Neurology, Medical School, National and Kapodistrian University of Athens, NKUA, Aeginition University Hospital, Athens, Greece; Research Unit of Radiology (G.V.), 2nd Department of Radiology, Medical School, National and Kapodistrian University of Athens, Greece; Neuroimmunology Unit (M.C.D.), Department of Pathophysiology, National and Kapodistrian University of Athens, Greece; and Department of Neurology (M.C.D.), Thomas Jefferson University, Philadelphia, PA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CD8-Positive T-LymphocytesKiller Cells, NaturalAdultDimethyl FumarateFemaleHerpes ZosterHumansImmunosuppressive AgentsMaleMultiple Sclerosis, Relapsing-RemittingYoung AdultDimethyl FumarateImmunosuppressive Agents

Identifiers

PMID34049996
PMCPMC8168045

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.