Evidence map›Paper›PMID 34049987›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Tumor Sink Effect in

Andrei Gafita, Hui Wang, Andrew Robertson, Wesley R Armstrong, Raphael Zaum, Manuel Weber, Farid Yagubbayli, Clemens Kratochwil, Tristan R Grogan, Kathleen Nguyen and 12 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 76 citations in OpenAlex.

  1. Clinical Trial Protocol for LPS-Boost: Intensified [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
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  2. Metformin and renal dosimetry in patients undergoing [European journal of nuclear medicine and molecular imaging · 2026
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  6. Baseline PSMA PET/CT Biomarkers for Patient Selection in [Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  7. Review
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  9. Article
  10. The tumour sink effect onCancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Observational
  11. Article
  12. Biodistribution and dosimetry of [European journal of nuclear medicine and molecular imaging · 2025
    Article
  13. Influence of fasting prior toEJNMMI research · 2024
    Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. First-in-human study of PSMA-targeting agent, [European journal of nuclear medicine and molecular imaging · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 8 institutions in 3 countries.

Andrei GafitaAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California; agafita@mednet.ucla.edu.
Hui WangDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Andrew RobertsonDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Wesley R ArmstrongAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California.
Raphael ZaumDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Manuel WeberDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium-University Hospital Essen, Essen, Germany.
Farid YagubbayliDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Clemens KratochwilDepartment of Nuclear Medicine, Heidelberg University Hospital, Heidelberg, Germany.
Tristan R GroganDepartment of Medicine Statistics Core, David Geffen School of Medicine, UCLA, Los Angeles, California.
Kathleen NguyenAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California.
Fernando NavarroDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Rouzbeh EsfandiariExcel Diagnostics and Nuclear Oncology Center, Houston, Texas.
Isabel RauscherDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Bjoern MenzeDepartment of Informatics, Technical University Munich, Munich, Germany.
David ElashoffDepartment of Medicine Statistics Core, David Geffen School of Medicine, UCLA, Los Angeles, California.
Ebrahim S DelpassandExcel Diagnostics and Nuclear Oncology Center, Houston, Texas.
Ken HerrmannDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium-University Hospital Essen, Essen, Germany.
Johannes CzerninAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California.
Michael S HofmanProstate Cancer Theranostics and Imaging Centre of Excellence, Molecular Imaging and Therapeutic Nuclear Medicine, Peter MacCallum Cancer Centre, and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.
Jeremie CalaisAhmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California.
Wolfgang P FendlerDepartment of Nuclear Medicine, University of Duisburg-Essen and German Cancer Consortium-University Hospital Essen, Essen, Germany.
Matthias EiberDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technical University Munich, Munich, Germany.
Klinikum rechts der Isar · DEUniversity of California, Los Angeles · USDeutschen Konsortium für Translationale Krebsforschung · DEExcel Diagnostics Imaging · USTechnical University of Munich · DEEssen University Hospital · DEPeter MacCallum Cancer Centre · AUUniversity Hospital Heidelberg · DE

Funding

Women's CancersP30CA016042 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Samuel Wheeler French · 1985 to 2026
$134.5M
UCLA SPORE in Brain CancerP50CA211015 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Yvonne Yu-Hsuan Chen · 2017 to 2026
$25.2M
NCI NIH HHS P30 CA016042NCI NIH HHS P50 CA211015
6 · The paper itself

Abstract

We aimed to systematically determine the impact of tumor burden on

Indexed as

Gallium RadioisotopesProstatic NeoplasmsEdetic AcidGallium IsotopesHumansMalePositron Emission Tomography Computed TomographyRetrospective StudiesTissue DistributionEdetic Acidgallium 68 PSMA-11Gallium IsotopesGallium RadioisotopesGa-PSMAPETprostate cancerPSMAradioligand therapytumor sink effect

Identifiers

PMID34049987
PMCPMC8805781
OpenAlexW3164434708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.