SynthesisBMJ open2021
Erectile dysfunction and penile rehabilitation after pelvic fracture: a systematic review and meta-analysis.
Synthesis in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Low-intensity shock wave therapy for penile rehabilitation in patients with erectile dysfunction following pelvic fracture urethral injury: a pilot study.International urology and nephrology · 2026Article
- Surgical Outcomes Following Subcoronal Degloving Repair in Penile Fracture: A Retrospective Case Series.Cureus · 2025Article
- Pelvic ring fracture and erectile dysfunction (PERFECD) - 3 year follow-up cross sectional study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- A Countertraction Closed Reduction Technique in Minimally Invasive Fixation of Recent Type C Pelvic Ring Injuries.Orthopaedic surgery · 2024Article
- Long-Term Follow-Up after Iliosacral Screw Fixation of Unstable Pelvic Ring Fractures.Journal of clinical medicine · 2024Article
- Correlation between traumatic pelvic ring injuries and sexual dysfunctions: a multicentric retrospective study.International orthopaedics · 2023Article
- Positive Predictive Factors for Urogenital Injuries in Severely Injured Patients with Pelvic and Spinal Fractures: Introducing the UPPS Scoring System.Medicina (Kaunas, Lithuania) · 2022Article
- Isolated penile corporeal cavernosal injury accompanying pelvic fracture after motor vehicle accident.Proceedings (Baylor University. Medical Center) · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the rate of erectile dysfunction (ED) after pelvic ring fracture (PRF).
designSystematic review and meta-analysis.
methodsA systematic literature search of the Cochrane, EMBASE, MEDLINE, Scopus and Web of Science Library databases was conducted in January 2020. Included were original studies performed on humans assessing ED after PRF according to the 5-item International Index of Erectile Function (IIEF-5) questionnaire and fracture classification following Young and Burgess, Tile or Arbeitsgemeinschaft für Osteosynthesefragen/Orthopedic Trauma Association. Furthermore, interventional cohort studies assessing the effect of penile rehabilitation therapy with phosphodiesterase-5-inhibitors (PDE-5-I) on IIEF-5 scores compared before and after treatment were included. Results were presented as forest plots of proportions of patients with ED after PRF or mean changes on IIEF-5 questionnaires before and after penile rehabilitation. Studies not included in the quantitative analysis were narratively summarised. Risk of bias assessment was conducted using the revised tool for the Quality Assessment on Diagnostic Accuracy Studies.
resultsThe systematic literature search retrieved 617 articles. Seven articles were included in the qualitative analysis and the meta-analysis. Pooled proportions revealed 37% of patients with ED after suffering any form of PRF (result on probability scale pr=0.37, 95% CI: 0.26 to 0.50). Patients after 3 months of penile rehabilitation therapy reported a higher IIEF-5 score than before (change score=6.5 points, 95% CI: 2.54 to 10.46, p value=0.0013).
conclusionDespite some heterogeneity and limited high-quality research, this study concludes that patients suffering from any type of PRF have an increased risk of developing ED. Oral intake of PDE-5-I for the purpose of penile rehabilitation therapy increases IIEF-5 scores and may relevantly influence quality-of-life in these patients. PROSPERO REGISTRATION NUMBER: CRD42020169699.
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