Evidence map›Paper›PMID 34049886›Full record

ArticleScience advances2021

Gestational low-dose BPA exposure impacts suprachiasmatic nucleus neurogenesis and circadian activity with transgenerational effects.

Dinushan Nesan, Kira M Feighan, Michael C Antle, Deborah M Kurrasch

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dinushan NesanDepartment of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.ORCID 0000-0003-3081-0795
Kira M FeighanDepartment of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.ORCID 0000-0003-4922-7137
Michael C AntleHotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.ORCID 0000-0001-5178-4683
Deborah M KurraschDepartment of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. kurrasch@ucalgary.ca.ORCID 0000-0002-9945-287X
University of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Critical physiological processes such as sleep and stress that underscore health are regulated by an intimate interplay between the endocrine and nervous systems. Here, we asked how fetal exposure to the endocrine disruptor found in common plastics, bisphenol A (BPA), causes lasting effects on adult animal behaviors. Adult mice exposed to low-dose BPA during gestation displayed notable disruption in circadian activity, social interactions, and associated neural hyperactivity, with some phenotypes maintained transgenerationally. Gestational BPA exposure increased vasopressin

Indexed as

Benzhydryl CompoundsPhenolsAnimalsBisphenol A CompoundsMiceNeurogenesisSuprachiasmatic NucleusBenzhydryl Compoundsbisphenol ABisphenol A CompoundsPhenols

Identifiers

PMID34049886
PMCPMC8163075
OpenAlexW3165438943

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.