Evidence map›Paper›PMID 34049880›Full record

ArticleScience advances2021

Two ligand-binding sites in CO-reducing V nitrogenase reveal a general mechanistic principle.

Michael Rohde, Konstantin Laun, Ingo Zebger, Sven T Stripp, Oliver Einsle

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 53 citations in OpenAlex.

  1. Review
  2. A Proposed Complete-Cycle Mechanism for Conversion of NChembiochem : a European journal of chemical biology · 2026
    Article
  3. Article
  4. Oxidatively Induced Reductive NJournal of the American Chemical Society · 2025
    Article
  5. The nitrogenase mechanism: new roles for the dangler?Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Review
  6. Biomimetic [MFeInorganic chemistry · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. On the Shoulders of Giants-Reaching for Nitrogenase.Molecules (Basel, Switzerland) · 2023
    Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. An FeAngewandte Chemie (International ed. in English) · 2022
    Article
  18. Article
  19. Review
  20. The Conversion of Carbon Monoxide and Carbon Dioxide by Nitrogenases.Chembiochem : a European journal of chemical biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Michael RohdeInstitute for Biochemistry, University of Freiburg, Albertstrasse 21, 79104 Freiburg, Germany.ORCID 0000-0002-2097-0149
Konstantin LaunInstitute of Chemistry, Technical University of Berlin, Straße des 17. Juni 135, 10623 Berlin, Germany.ORCID 0000-0001-7617-0186
Ingo ZebgerInstitute of Chemistry, Technical University of Berlin, Straße des 17. Juni 135, 10623 Berlin, Germany.ORCID 0000-0002-6354-3585
Sven T StrippInstitute of Experimental Physics, Department of Physics, Free University of Berlin, Arnimallee 14, 14195 Berlin, Germany.ORCID 0000-0002-8412-0258
Oliver EinsleInstitute for Biochemistry, University of Freiburg, Albertstrasse 21, 79104 Freiburg, Germany. einsle@biochemie.uni-freiburg.de.ORCID 0000-0001-8722-2893
Technische Universität Berlin · DEUniversity of Freiburg · DEFreie Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Besides its role in biological nitrogen fixation, vanadium-containing nitrogenase also reduces carbon monoxide (CO) to hydrocarbons, in analogy to the industrial Fischer-Tropsch process. The protein yields 93% of ethylene (C

Identifiers

PMID34049880
PMCPMC8163085
OpenAlexW3165731882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.