Evidence map›Paper›PMID 34049877›Full record

ReviewScience advances2021

Molecular mechanisms of metabotropic GABA

Hamidreza Shaye, Benjamin Stauch, Cornelius Gati, Vadim Cherezov

Open access · goldAbstract readReview
In one paragraph

Review in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

  1. Potential TMS biomarkers for GABAAlcohol, clinical & experimental research · 2025
    Pooled it
  2. Review
  3. Article
  4. Review
  5. GABAExperimental physiology · 2026
    Article
  6. Vagal GABAergic signaling in autonomic control of cardiometabolic function.American journal of physiology. Cell physiology · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. GABAeNeuro · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hamidreza ShayeDepartment of Chemistry, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0002-8670-1259
Benjamin StauchDepartment of Chemistry, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0001-7626-2021
Cornelius GatiBridge Institute, Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0003-3693-7009
Vadim CherezovDepartment of Chemistry, University of Southern California, Los Angeles, CA, USA. cherezov@usc.edu.ORCID 0000-0002-5265-3914
University of Southern California · US

Funding

Structural Biology Of G Protein-Coupled ReceptorsR35GM127086 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Vadim Cherezov · 2018 to 2026
$3.6M
NIGMS NIH HHS R35 GM127086
6 · The paper itself

Abstract

Metabotropic γ-aminobutyric acid G protein-coupled receptors (GABA

Indexed as

BrainReceptors, GABA-Bgamma-Aminobutyric AcidLigandsgamma-Aminobutyric AcidLigandsReceptors, GABA-B

Identifiers

PMID34049877
PMCPMC8163086
OpenAlexW3163960069

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.