Evidence map›Paper›PMID 34049526›Full record

ArticleBMC public health2021

Identifying US County-level characteristics associated with high COVID-19 burden.

Daniel Li, Sheila M Gaynor, Corbin Quick, Jarvis T Chen, Briana J K Stephenson, Brent A Coull, Xihong Lin

Abstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Using wastewater to overcome health disparities among rural residents.Geoforum; journal of physical, human, and regional geosciences · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Spatial Clustering of County-Level COVID-19 Rates in the U.S.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel LiDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, 655 Huntington Ave, Building II, Room 419, Boston, MA, 02115, USA.
Sheila M GaynorDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, 655 Huntington Ave, Building II, Room 419, Boston, MA, 02115, USA.
Corbin QuickDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, 655 Huntington Ave, Building II, Room 419, Boston, MA, 02115, USA.
Jarvis T ChenDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Briana J K StephensonDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, 655 Huntington Ave, Building II, Room 419, Boston, MA, 02115, USA.
Brent A CoullDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, 655 Huntington Ave, Building II, Room 419, Boston, MA, 02115, USA.
Xihong LinDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, 655 Huntington Ave, Building II, Room 419, Boston, MA, 02115, USA. xlin@hsph.harvard.edu.

Funding

Translating Molecular and Clinical Data to Population Lung Cancer Risk AssessmentU19CA203654 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Rayjean J. Hung · 2017 to 2026
$23.7M
Interdisciplinary training: Statistical Genetics/Genomics and Computational BiologyT32GM135117 · NIGMS · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Curtis Huttenhower, XIHONG LIN · 2020 to 2026
$3.1M
Improving statistical methods for small area estimates of public health indicators and demographic characteristicsR01HD092580 · NICHD · EMORY UNIVERSITY · PI Lance A Waller · 2018 to 2026
$2.3M
NICHD NIH HHS R01 HD092580NIGMS NIH HHS T32 GM135117
6 · The paper itself

Abstract

backgroundIdentifying county-level characteristics associated with high coronavirus 2019 (COVID-19) burden can help allow for data-driven, equitable allocation of public health intervention resources and reduce burdens on health care systems.

methodsSynthesizing data from various government and nonprofit institutions for all 3142 United States (US) counties, we studied county-level characteristics that were associated with cumulative and weekly case and death rates through 12/21/2020. We used generalized linear mixed models to model cumulative and weekly (40 repeated measures per county) cases and deaths. Cumulative and weekly models included state fixed effects and county-specific random effects. Weekly models additionally allowed covariate effects to vary by season and included US Census region-specific B-splines to adjust for temporal trends.

resultsRural counties, counties with more minorities and white/non-white segregation, and counties with more people with no high school diploma and with medical comorbidities were associated with higher cumulative COVID-19 case and death rates. In the spring, urban counties and counties with more minorities and white/non-white segregation were associated with increased weekly case and death rates. In the fall, rural counties were associated with larger weekly case and death rates. In the spring, summer, and fall, counties with more residents with socioeconomic disadvantage and medical comorbidities were associated greater weekly case and death rates.

conclusionsThese county-level associations are based off complete data from the entire country, come from a single modeling framework that longitudinally analyzes the US COVID-19 pandemic at the county-level, and are applicable to guiding government resource allocation policies to different US counties.

Indexed as

COVID-19Social SegregationHumansPandemicsRural PopulationSARS-CoV-2United StatesCOVID-19Health disparitiesResource allocation

Identifiers

PMID34049526
PMCPMC8162162

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.