Evidence map›Paper›PMID 34049504›Full record

ArticleBMC neurology2021

Graves' disease with anti-GQ1b antibody syndrome: a rare case report.

Tao Liang, Zhiwei Zhou, Xiaolin Hu, Zhong Luo

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tao Liang *Department of Neurology, the Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Zhiwei Zhou *Department of Neurology, the Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Xiaolin HuDepartment of Surgery Spine, the Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Zhong LuoDepartment of Neurology, the Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China. 1494676932@qq.com.ORCID http://orcid.org/0000-0003-4084-2424
Zunyi Medical University · CN

Funding

National Natural Science Foundation of China 81760225
6 · The paper itself

Abstract

backgroundGraves' disease and anti-GQ1b antibody syndrome are both autoimmune diseases, and there have been few reports on whether there is a correlation between the two. In this study, we present the case of a woman who was diagnosed with Graves' disease and anti-GQ1b antibody syndrome in succession. CASE PRESENTATION: The chief complaints of this patient were limb weakness and blurred vision. Graves' disease was diagnosed by examination of thyroid function and thyroid autoantibodies, but the clinical symptoms were not relieved after antihyperthyroidism treatment. Finally, it was found that Graves' disease was complicated by anti-GQ1b antibody syndrome, and the symptoms were relieved after treatment with glucocorticoids and intravenous immunoglobulin. We also explored the possible mechanism of these diseases through a literature review.

conclusionsWe report a rare case of the cooccurrence of Graves' disease and anti-GQ1b antibody syndrome. Immune dysregulation might be the pathogenesis of the association, but there is no precise supporting evidence, and more research is needed.

Indexed as

AutoantibodiesAutoimmune DiseasesGraves DiseaseFemaleGangliosidesHumansAutoantibodiesGangliosidesGQ1b gangliosideExtraocular paralysis, case reportGQ1b antibodyGraves’ diseaseLimb weakness

Identifiers

PMID34049504
PMCPMC8161606
OpenAlexW3164645064

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.