ArticleBMC cardiovascular disorders2021
Waist to height ratio is associated with an increased risk of mortality in Chinese patients with heart failure with preserved ejection fraction.
Article in BMC cardiovascular disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk Prediction Models and Novel Prognostic Factors for Heart Failure with Preserved Ejection Fraction: A Systematic and Comprehensive Review.Current pharmaceutical design · 2023Pooled it
- Near-universal prevalence of central adiposity in heart failure with preserved ejection fraction: the PARAGON-HF trial.European heart journal · 2025Trial
- Review
- Comprehensive Analysis of the Relationship Between Cardiometabolic Index and Coronary Heart Disease.International journal of general medicine · 2026Article
- Central Adiposity or Hypertension: Which Drives Heart Failure With a Preserved Ejection Fraction?Journal of the American College of Cardiology · 2025Review
- Is Type 2 Diabetes a Modifiable Risk Factor for the Evolution and Progression of Heart Failure With a Preserved Ejection Fraction?Journal of the American College of Cardiology · 2025Review
- Article
- Is systemic inflammation a missing link between cardiometabolic index with mortality? Evidence from a large population-based study.Cardiovascular diabetology · 2024Article
- Association between triglyceride glucose-waist to height ratio and coronary heart disease: a population-based study.Lipids in health and disease · 2024Article
- Association between cardiometabolic index and congestive heart failure among US adults: a cross-sectional study.Frontiers in cardiovascular medicine · 2024Article
- Heart Failure Prevalence Rates and Its Association with Other Cardiovascular Diseases and Chronic Kidney Disease: SIMETAP-HF Study.Journal of clinical medicine · 2023Article
- The weight-adjusted-waist index predicts all-cause and cardiovascular mortality in general US adults.Clinics (Sao Paulo, Brazil) · 2023Article
- Association Between Visceral Fat, Blood Pressure and Arterial Stiffness in Patients with HFpEF: A Mediation Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Impact of theFrontiers in pharmacology · 2022Article
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Authors and funding
9 authors.
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Abstract
backgroundAbdominal obesity as a predominant comorbidity has played a key role in the incidence and worsening of heart failure with preserved ejection fraction (HFpEF), and waist-to-height ratio (WHtR) behaves better than waist circumference or body mass index in evaluating abdominal obesity. While the association between WHtR and all-cause death in Chinese patients with HFpEF remains unclear.
methodsPatients with stable HFpEF (N = 2041) who presented to our hospital from January 2008 to July 2019 were divided into low-WHtR (< 0.5, N = 378) and high-WHtR (≥ 0.5, N = 1663). Multivariable Cox proportional-hazard models were used to examine the association of WHtR with all-cause death.
resultsThe average age was 76.63 ± 11.44 years, and the mean follow-up was 4.53 years. During follow-up, 185 patients (9.06%) reached the primary outcome of all-cause death. As for the secondary outcome, 79 patients (3.87%) experienced cardiovascular death, 106 (5.19%) had non-cardiovascular death, and 94 (4.61%) had heart failure rehospitalization. After multivariable adjustment, a higher WHtR was significantly associated with the increased risks of all-cause death [adjusted hazard ratios (HR) 1.91, 95% confidence interval (CI) 1.06-3.45, p = 0.032], cardiovascular death (adjusted HR 2.58; 95% CI 1.01-6.67, p = 0.048), and HF rehospitalization (adjusted HR 3.04; 95% CI 1.26-7.31, p = 0.013).
conclusionsHigher WHtR is an independent risk factor for all-cause death in Chinese patients with HFpEF.
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