Evidence map›Paper›PMID 34049388›Full record

ArticleThe Journal of nutrition2021

Consumption of Preserved Egg Is Associated with Modestly Increased Risk of Nonalcoholic Fatty Liver Disease in Chinese Adults.

Shunming Zhang, Ge Meng, Qing Zhang, Li Liu, Zhanxin Yao, Hongmei Wu, Yeqing Gu, Yawen Wang, Tingjing Zhang, Xuena Wang and 9 more

Abstract read
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In one paragraph

Article in The Journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Shunming ZhangNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Ge MengNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Qing ZhangHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Li LiuHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Zhanxin YaoNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Hongmei WuNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Yeqing GuInstitute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
Yawen WangNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Tingjing ZhangNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Xuena WangNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Juanjuan ZhangNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Shaomei SunHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Xing WangHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Ming ZhouHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Qiyu JiaHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Kun SongHealth Management Centre, Tianjin Medical University General Hospital, Tianjin, China.
Yaogang WangNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Lu QiDepartment of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA.ORCID 0000-0002-8041-7791
Kaijun NiuNutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.ORCID 0000-0002-8772-2481

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough preserved egg is a traditional Chinese delicacy widely consumed in China and Southeast Asian countries, whether habitual preserved egg consumption is associated with nonalcoholic fatty liver disease (NAFLD) remains unknown.

objectivesThis study aimed to examine the association between preserved egg consumption and risk of NAFLD in a cohort of Chinese adults.

methodsThis prospective cohort study included 15,883 participants aged 19-88 y (58% women) from the TCLSIH (Tianjin Chronic Low-grade Systemic Inflammation and Health) cohort study who were free of liver diseases, cancer, and cardiovascular disease at baseline. Preserved egg consumption was assessed using an FFQ at baseline. NAFLD was diagnosed by transabdominal sonography during an annual health examination. Multivariable Cox proportional hazards regression models were used to calculate HRs and 95% CIs across categories of preserved egg consumption.

resultsDuring 56,002 person-years of follow-up, 3683 first incident cases of NAFLD were recorded. After adjustment for sociodemographic characteristics, lifestyle risk factors, total energy intake, egg intake, and eating patterns, the multivariable HRs (95% CIs) of incident NAFLD according to categories of preserved egg consumption were 1.00 (reference) for never, 1.05 (0.98, 1.14) for <1 time/wk, 1.09 (0.96, 1.24) for 1 time/wk, and 1.26 (1.09, 1.46) for ≥2 times/wk (P-trend < 0.01). The results were robust to a series of sensitivity analyses.

conclusionsHabitual preserved egg consumption is associated with a modestly higher risk of NAFLD among the Chinese adult population. The mechanism underlying this association warrants further research.This trial was registered at www.umin.ac.jp/ctr/ as UMIN000027174.

Indexed as

Non-alcoholic Fatty Liver DiseaseAdultChinaCohort StudiesFeeding BehaviorFemaleHumansMaleProspective StudiesRisk FactorsChinacohort studyfatty liverleadNAFLDpreserved egg

Identifiers

PMID34049388

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.