Evidence map›Paper›PMID 34049261›Full record

ReviewCurrent opinion in virology2021

SARS-CoV-2 vaccines - the biggest medical research project of the 21st century.

Drishya Kurup, Matthias J Schnell

Abstract readReview
In one paragraph

Review in Current opinion in virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Current vaccine strategies against SARS-CoV-2: Promises and challenges.The Journal of allergy and clinical immunology · 2022
    Review
  6. Article
  7. Cutaneous findings following COVID-19 vaccination: review of world literature and own experience.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Drishya KurupDepartment of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA, United States.
Matthias J SchnellDepartment of Microbiology and Immunology, Thomas Jefferson University, Philadelphia, PA, United States; Jefferson Vaccine Center, Thomas Jefferson University, Philadelphia, PA, United States. Electronic address: Matthias.Schnell@jefferson.edu.

Funding

Toward a protective Covid-19 vaccine utilizing an established vector platformR21AI158044 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI SCHNELL, MATTHIAS JOHANNES · 2020 to 2020
$429k
NIAID NIH HHS R21 AI158044
6 · The paper itself

Abstract

SARS-CoV-2 has been detected in more than 141 million people and caused more than 3 million deaths worldwide. To reduce the additional loss of millions of lives until natural immunity is reached, researchers have focused on the only known method to stop the COVID-19 pandemic: vaccines. The pandemic has propelled high-speed vaccine development, some based on novel technology previously not utilized in the vaccine field. The new technology opens new possibilities and comes with challenges because the long-term performance of the new platforms is unknown. Here we review the current leading vaccine candidates against COVID-19 and outline the advantages and disadvantages as well as the unknowns of each candidate.

Indexed as

Biomedical ResearchAdenoviridaeCOVID-19COVID-19 VaccinesHumansmRNA VaccinesMutationSARS-CoV-2Vaccines, InactivatedVaccines, SubunitVaccines, SyntheticCOVID-19 VaccinesmRNA VaccinesVaccines, InactivatedVaccines, SubunitVaccines, Synthetic

Identifiers

PMID34049261
PMCPMC8096205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.