Evidence map›Paper›PMID 34049099›Full record

ArticleDrug and alcohol dependence2021

The role of alcohol and other drugs on emergency department traumatic injury mortality in the United States.

Charles J DiMaggio, Jacob B Avraham, Spiros G Frangos, Katherine Keyes

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Detecting Ethanol Intoxication and Impairment Using Wearable Biosensors.Proceedings of the ... Annual Hawaii International Conference on System Sciences. Annual Hawaii International Conference on System Sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Charles J DiMaggioDepartment of Surgery, Division of Trauma and Acute Care Surgery, New York University School of Medicine, New York, NY, United States; Department of Population Health, New York University School of Medicine, New York, NY, United States.
Jacob B AvrahamDepartment of Surgery, Division of Trauma and Acute Care Surgery, NorthShore University HealthSystem, Evanston, IL, United States. Electronic address: javraham@northshore.org.
Spiros G FrangosDepartment of Surgery, Division of Trauma and Acute Care Surgery, New York University School of Medicine, New York, NY, United States.
Katherine KeyesDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, NY, United States.
New York University · USColumbia University · USNorthShore University HealthSystem · US

Funding

Data Integration and Advanced Statistical Modeling to Describe and Control Pediatric Pedestrian Injuries in The United StatesR01HD087460 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DIMAGGIO, CHARLES · 2016 to 2018
$984k
NICHD NIH HHS R01 HD087460
6 · The paper itself

Abstract

backgroundAlcohol and other drugs (AOD) increase the risk of traumatic injury occurring, but data suggest a protective benefit in preventing trauma-related mortality. The objective of this study is to describe the epidemiology of AOD-related traumatic injury in the US over a recent 7 year period and assess the interaction of traumatic injury and AOD on pre-admission fatality on both an additive scale using incidence contrasts and on a statistical multiplicative scale using survey-adjusted logistic regression.

methodsUsing the National Emergency Department Sample (NEDS), we describe the epidemiology of alcohol and substance-related emergency department traumatic injury over a recent period. AOD-related injury was assessed using survey-adjusted counts and means. Ratio estimates and differences were calculated using simulations based on survey-adjusted counts and standard errors. Differences in trends over time were evaluated by comparing the slopes of linear regression equations with year as the predictor variable.

resultsAlcohol and substance-related emergency department injury discharges increased 9.8 % during the study period. There was a statistically significant interaction between traumatic injury death and AOD on both an additive scale and multiplicative scale. (Odds Ratio for interaction term = 1.76, 95 % CI = 1.53, 2.03).

conclusionsAOD use does not provide a protective benefit in the setting of trauma, but rather is an important contributor to traumatic injury mortality.

Indexed as

Emergency Service, HospitalPharmaceutical PreparationsEthanolHumansIncidenceOdds RatioUnited StatesEthanolPharmaceutical PreparationsAlcoholDrugsEmergency departmentInjuryTrauma

Identifiers

PMID34049099
PMCPMC8282716
OpenAlexW3164487515

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.