Evidence map›Paper›PMID 34048701›Full record

ArticleCell2021

Interdisciplinary approaches are fundamental to decode the biology of adversity.

Yvonne Baumer, Tiffany M Powell-Wiley

Registry-linked trialAbstract read
In one paragraph

Article in Cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06386380 (Adversity and Its Association With the Development and Expression of Rheumatic Diseases), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06386380 unknown statusnot on this mapstarted 2024, after this paper: background citation

Adversity and Its Association With the Development and Expression of Rheumatic Diseases

TypeobservationalSponsorNational Institute of Medical Sciences and Nutrition, Salvador ZubiranRan2024 to 2026Enrolled110ConditionsRhA - Rheumatoid ArthritisArmsRheumatic diseases Mistreatment Scale (RDMS), Routine assessment of patient index data 3 (RAPID-3), Health Assessment Questionnaire (HAQ), WHOQOL-BREF, Depression, Anxiety and Stress Scale (DASS-21)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Reply to Füller et al.: Exome-wide genetic associations with socioeconomic status and their pleiotropy among health outcomes.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yvonne BaumerSocial Determinants of Obesity and Cardiovascular Risk Laboratory, Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA.
Tiffany M Powell-WileySocial Determinants of Obesity and Cardiovascular Risk Laboratory, Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, USA; Intramural Research Program, National Institute on Minority Health and Health Disparities, NIH, Bethesda, MD, USA. Electronic address: tiffany.powell-wiley@nih.gov.

Funding

Tailoring Mobile Health Technology to Reduce Obesity and ImproveCardiovascular Health in Resource-Limited Neighborhood Environments: A Multi-Level, Community-Based Physical Activity InterventionZIAHL006225 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI POWELL-WILEY, TIFFANY · 2017 to 2025
$9.7M
Cardiovascular Health and Needs Assessment in Washington D.C.ZIAHL006168 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI POWELL-WILEY, TIFFANY · 2013 to 2025
$8.1M
Pilot Study for Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in WomenZIAHL006252 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI POWELL-WILEY, TIFFANY · 2020 to 2025
$5.7M
Intramural NIH HHS ZIA HL006168Intramural NIH HHS ZIA HL006225Intramural NIH HHS ZIA HL006252
6 · The paper itself

Abstract

The COVID-19 pandemic has highlighted structural inequalities and racism promoting health disparities among communities of color. Taking cardiovascular disease as an example, we provide a framework for multidisciplinary efforts leveraging translational and epidemiologic approaches to decode the biological impacts of inequalities and racism and develop targeted interventions that promote health equity.

Indexed as

Health EquityRacismCardiovascular DiseasesCOVID-19Gene Expression RegulationHealth PromotionHumansHypothalamo-Hypophyseal SystemRisk FactorsStress, PhysiologicalSympathetic Nervous System

Identifiers

PMID34048701
PMCPMC8493648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.