Evidence map›Paper›PMID 34048545›Full record

ArticleDatabase : the journal of biological databases and curation2021

dbGENVOC: database of GENomic Variants of Oral Cancer, with special reference to India.

Sanchari Pradhan, Subrata Das, Animesh K Singh, Chitrarpita Das, Analabha Basu, Partha P Majumder, Nidhan K Biswas

Open access · goldAbstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sanchari PradhanHuman Genetics Unit, National Institute of Biomedical Genomics, Kalyani, West Bengal 741251, India.
Subrata DasHuman Genetics Unit, National Institute of Biomedical Genomics, Kalyani, West Bengal 741251, India.
Animesh K SinghHuman Genetics Unit, National Institute of Biomedical Genomics, Kalyani, West Bengal 741251, India.
Chitrarpita DasHuman Genetics Unit, National Institute of Biomedical Genomics, Kalyani, West Bengal 741251, India.
Analabha BasuHuman Genetics Unit, National Institute of Biomedical Genomics, Kalyani, West Bengal 741251, India.
Partha P MajumderHuman Genetics Unit, National Institute of Biomedical Genomics, Kalyani, West Bengal 741251, India.
Nidhan K BiswasHuman Genetics Unit, National Institute of Biomedical Genomics, Kalyani, West Bengal 741251, India.ORCID 0000-0001-7960-3290
National Institute of Biomedical Genomics · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral cancer is highly prevalent in India and is the most frequent cancer type among Indian males. It is also very common in southeast Asia. India has participated in the International Cancer Genome Consortium (ICGC) and some national initiatives to generate large-scale genomic data on oral cancer patients and analyze to identify associations and systematically catalog the associated variants. We have now created an open, web-accessible database of these variants found significantly associated with Indian oral cancer patients, with a user-friendly interface to enable easy mining. We have value added to this database by including relevant data collated from various sources on other global populations, thereby providing opportunities of comparative geographical and/or ethnic analyses. Currently, no other database of similar nature is available on oral cancer. We have developed Database of GENomic Variants of Oral Cancer, a browsable online database framework for storage, retrieval and analysis of large-scale data on genomic variants and make it freely accessible to the scientific community. Presently, the web-accessible database allows potential users to mine data on ∼24 million clinically relevant somatic and germline variants derived from exomes (n = 100) and whole genomes (n = 5) of Indian oral cancer patients; all generated by us. Variant data from The Cancer Genome Atlas and data manually curated from peer-reviewed publications were also incorporated into the database for comparative analyses. It allows users to query the database by a single gene, multiple genes, multiple variant sites, genomic region, patient ID and pathway identities. Database URL: http://research.nibmg.ac.in/dbcares/dbgenvoc/.

Indexed as

GenomicsMouth NeoplasmsDatabases, FactualExomeHumansIndiaMale

Identifiers

PMID34048545
PMCPMC8163239
OpenAlexW3163998883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.