ReviewContinuum (Minneapolis, Minn.)2021
Headache in Children and Adolescents.
Review in Continuum (Minneapolis, Minn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Biomarkers in headaches as a potential solution to simplify differential diagnosis of primary headache disorders: a systematic review.The journal of headache and pain · 2025Pooled it
- The effectiveness of aerobic exercise and neck exercises in pediatric migraine treatment: a randomized controlled single-blind study.Irish journal of medical science · 2024Trial
- Celiac Disease and the Nervous System: A Comprehensive Overview of Neurological Manifestations and Underlying Mechanisms.Neuromolecular medicine · 2026Review
- Pediatric migraine: Neurodevelopmental mechanisms, clinical phenotypes, and modern therapeutics.World journal of clinical pediatrics · 2026Review
- Pediatric Headache in the Age of Social Media: A Topical Review.Current pain and headache reports · 2026Review
- Article
- PRIME-Teen-Treatment Persistence and Outcomes Associated with CGRP Monoclonal Antibodies Compared with Conventional Oral Preventives in Adolescents with High-Burden Migraine: An Exploratory Real-World Analysis from the German Pain e-Registry (GPeR).Journal of clinical medicine · 2026Article
- Clinical predictors of propranolol responsiveness in pediatric migraine: a prospective observational study.Journal of oral & facial pain and headache · 2026Observational
- Longitudinal changes in neurometabolites in pediatric migraine across child development: a pilot study.Scientific reports · 2026Article
- Digital Media Use in Adolescents with Migraine: A Topical Review.Current pain and headache reports · 2025Review
- Exposure Matching Using Population Pharmacokinetic Modeling and Simulation to Support Rimegepant Dose Selection for Pediatric Patients With Migraine.Clinical and translational science · 2025Article
- Headache diagnosis in children and adolescents: validation of the Italian version of the HARDSHIP questionnaire.The journal of headache and pain · 2025Article
- Quality of life among pediatric and adolescent patients with migraine: A cross-sectional study.Journal of family medicine and primary care · 2025Article
- Demographic and clinical characteristics of children and adolescents with headache and/or dizziness and hemodynamic responses to head-up tilt test.Italian journal of pediatrics · 2025Article
- New-onset headache after transcatheter atrial septal defect closure: a systematic review.Indian journal of thoracic and cardiovascular surgery · 2025Review
- Current Trends in Pediatric Migraine: Clinical Insights and Therapeutic Strategies.Brain sciences · 2025Review
- Episodic Migraine in the Pediatric Population: Behavioral Therapies and other Non-Pharmacological Treatment Options.Current pain and headache reports · 2025Review
- Look at My Body: It Tells of Suffering-Understanding Psychiatric Pathology in Patients Who Suffer from Headaches, Restrictive Eating Disorders, or Non-Suicidal Self-Injuries (NSSIs).Pediatric reports · 2025Article
- Impact of temporomandibular disorder symptoms among 15-year-old girls.Acta odontologica Scandinavica · 2024Article
- New Daily Persistent Headache in the Pediatric and Adolescent Population: An Updated Review.Life (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
purpose of reviewThis article reviews the approach to a child or adolescent with headache, the criteria for common diagnoses, and the evidence base for treatments. RECENT
findingsThe guidelines for acute and preventive treatment of migraine were updated in 2019. These guidelines summarize the available evidence and outline the questions that should be addressed in future research. The US Food and Drug Administration (FDA) approval of several new classes of drugs and devices to treat adult migraine in the past few years has resulted in ongoing or planned pediatric trials. SUMMARY: Headache is a common symptom in children, and it is important to take a detailed history and perform a thorough physical examination to make the diagnosis. Nearly 1 in 10 children experience recurrent headaches due to migraine, which cause significant impairment in school performance and quality of life. The acute and preventive treatments that are currently available will help at least two-thirds of children with migraine, and several trials of new therapies offer hope for the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.