Evidence map›Paper›PMID 34048321›Full record

ArticleThe neuroradiology journal2021

Possible additional MRI markers for critical brain swelling with increased intracranial pressure in children?

Thierry Agm Huisman, Misun Hwang, Gunes Orman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The neuroradiology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Thierry Agm HuismanEdward B Singleton Department of Radiology, Texas Children's Hospital and Baylor College of Medicine, USA.
Misun HwangDepartment of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania, USA.
Gunes OrmanEdward B Singleton Department of Radiology, Texas Children's Hospital and Baylor College of Medicine, USA.ORCID https://orcid.org/0000-0003-2684-3957
Baylor College of Medicine · USChildren's Hospital of Philadelphia · US

Funding

Novel Ultrasound Indices of Intracranial Pressure and Brain Ischemia in Neonatal HydrocephalusR01NS119473 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI Misun Hwang · 2020 to 2026
$4.0M
NINDS NIH HHS R01 NS119473
6 · The paper itself

Abstract

A retrospective study was performed evaluating the volume and T2/T1 signal intensity of orbital fat in five children diagnosed with severe global brain swelling and confirmed cessation of cerebral perfusion. Imaging showed a volume increase (five of five) and a heterogeneous T2-hypointensity of orbital fat (four of five). This preliminary study suggests that swelling and T2-hypointensity of orbital fat may be a marker of global brain swelling and/or increased intracranial pressure.

Indexed as

Brain EdemaBrainChildHumansIntracranial PressureMagnetic Resonance ImagingRetrospective StudiesBrain deathbrain swellingorbital fat

Identifiers

PMID34048321
PMCPMC8649183
OpenAlexW3164252447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.