Evidence map›Paper›PMID 34048011›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

A Murine Model of Full-Thickness Scald Burn Injury with Subsequent Wound and Systemic Bacterial Infection.

Antonio Hernandez, Naeem K Patil, Julia K Bohannon

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Determination of Burn Size in Mouse Models of Burn Injury: A Scoping Review of Studies Leveraging Scald and Contact Burns.Journal of burn care & research : official publication of the American Burn Association · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Evolutionary andCurrent research in microbial sciences · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Antonio HernandezDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA.
Naeem K PatilDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA.
Julia K BohannonDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA. julia.k.bohannon@vumc.org.
Vanderbilt University Medical Center · US

Funding

Protection Against Nosocomial Infections After Severe Burn Injury Through Trained ImmunityR35GM141927 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Julia K. Bohannon · 2021 to 2026
$2.4M
Enhancing Resistance to Infection after Burn Injury with TLR AgonistsR01GM121711 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BOHANNON, JULIA K. · 2017 to 2021
$1.6M
Enhancement of Innate Anti-Microbial Immunity Using Novel Synthetic TLR4 AgonistsK08GM123345 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HERNANDEZ, ANTONIO · 2017 to 2020
$699k
NIGMS NIH HHS K08 GM123345NIGMS NIH HHS R01 GM121711NIGMS NIH HHS R35 GM141927
6 · The paper itself

Abstract

Infection is the leading cause of death and prolonged hospitalization in severely burned patients that survive the acute phase of injury. Here we describe a murine model of severe burn injury followed by subsequent postburn infection, both local and systemic, that leads to sepsis. A detailed description of the full-thickness scald burn procedure is provided, followed by description of infection with two common burn-associated nosocomial pathogens, Pseudomonas aeruginosa and Staphylococcus aureus.

Indexed as

AnimalsBurnsDisease Models, AnimalFemaleMaleMiceMice, Inbred BALB CPseudomonas aeruginosaPseudomonas InfectionsSepsisStaphylococcal InfectionsStaphylococcus aureusWound InfectionBurnNosocomial infectionPseudomonas aeruginosaSepsisStaphylococcus aureus

Identifiers

PMID34048011
PMCPMC9057493
OpenAlexW3164831442

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.