Evidence map›Paper›PMID 34047924›Full record

ArticleJournal of general internal medicine2021

Benzodiazepine Prescribing from VA and Medicare to Dually Enrolled Older Veterans: A Retrospective Cohort Study.

Lianlian Lei, Julie Strominger, Ilse R Wiechers, H Myra Kim, Frederic C Blow, Amy S B Bohnert, Lillian Min, Sarah L Krein, Donovan T Maust

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Characteristics of incident benzodiazepine recipients among US veterans with posttraumatic stress disorder.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2025
    Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lianlian LeiDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Julie StromingerCenter for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Ilse R WiechersNortheast Program Evaluation Center, Office of Mental Health and Suicide Prevention, Department of Veterans Affairs, West Haven, CT, USA.
H Myra KimCenter for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Frederic C BlowDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
Amy S B BohnertCenter for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Lillian MinCenter for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Sarah L KreinCenter for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA.
Donovan T MaustDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA. maustd@umich.edu.ORCID 0000-0003-4740-2640

Funding

Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
HSRD VA I01 HX002340HSRD VA IK6 HX003399NIA NIH HHS P30 AG024824VA IIR 16-210
6 · The paper itself

Abstract

backgroundThere has been a reduction in BZD prescribing in the Veterans Affairs (VA) health care system since 2013. It is unknown whether the decline in VA-dispensed BZDs has been offset by Medicare Part D prescriptions.

objectivesTo examine (1) whether, accounting for Part D, declines in BZD prescribing to older Veterans remain; (2) patient characteristics associated with obtaining BZDs outside VA and facility variation in BZD source (VA only, VA and Part D, Part D only).

designRetrospective cohort study with mixed effects multinomial logistic model examining characteristics associated with BZD source. PATIENTS: A total of 1,746,278 Veterans aged ≥65 enrolled in VA and Part D, 2013-2017. MAIN MEASURES: BZD prescription prevalence and source. KEY

resultsFrom January 2013 to June 2017, the quarterly prevalence of older Veterans with Part D filling BZD prescriptions through the VA declined from 5.2 to 3.1% (p<0.001) or, accounting for Part D, from 10.0 to 7.7% (p<0.001). Among those prescribed BZDs between July 2016 and June 2017, 37.0%, 10.2%, and 52.8% received prescriptions from VA only, both VA and Part D, or Part D only, respectively. Older age was associated with higher odds of obtaining BZDs through Part D (e.g., compared to those 65-74, Veterans ≥85 had adjusted odds ratio [AOR] for Part D vs. VA only of 1.8 [95% highest posterior density interval (HPDI), 1.69, 1.86]). Veterans with substance use disorders accounted for few BZD prescriptions from any source but were associated with higher odds of prescriptions through Part D (e.g., alcohol use disorder AOR for Part D vs. VA alone: 1.9 [95% HPDI, 1.63, 2.11])

conclusionsThe decline in BZD use by older Veterans with Part D coverage remained after accounting for Part D, but the majority of BZD prescriptions came from Medicare. Further reducing BZD prescribing to older Veterans should consider prescriptions from community sources.

Indexed as

Medicare Part DVeteransAgedBenzodiazepinesDrug PrescriptionsHumansRetrospective StudiesUnited StatesUnited States Department of Veterans AffairsBenzodiazepinesbenzodiazepineMedicareVeteran

Identifiers

PMID34047924
PMCPMC8642498

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.