Evidence map›Paper›PMID 34047921›Full record

Trial reportJournal of general internal medicine2022

A Centralized Program with Stepped Support Increases Adherence to Colorectal Cancer Screening Over 9 Years: a Randomized Trial.

Beverly B Green, Melissa L Anderson, Andrea J Cook, Jessica Chubak, Sharon Fuller, Richard T Meenan, Sally W Vernon

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00697047 (Systems of Support to Increase Colon Cancer Screening and Follow-up), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00697047 nacompletednot on this map

Systems of Support to Increase Colon Cancer Screening and Follow-up

TypeinterventionalSponsorKaiser PermanenteRan2008 to 2019Enrolled4,653ConditionsColorectal CancerArmsAutomated Mailing, Automated Mailing Plus Assisted, Auto Plus Assisted Plus Navigation
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Longitudinal Adherence With Stool-Based Testing for Colorectal Cancer Screening in Four United States Health Systems.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Article
  2. Review
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Beverly B GreenKaiser Permanente Washington, Seattle, WA, USA. Bev.B.Green@kp.org.ORCID 0000-0003-3040-3436
Melissa L AndersonKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Andrea J CookKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Jessica ChubakKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Sharon FullerKaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
Richard T MeenanCenter for Health Research, Kaiser Permanente Northwest, Portland, OR, USA.
Sally W VernonUniversity of Texas School of Public Health, Houston, TX, USA.

Funding

Systems of Support (SOS) to Increase Colon Cancer Screening and Follow-upR01CA121125 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI GREEN, BEVERLY BETH · 2007 to 2017
$8.0M
NCI NIH HHS R01 CA121125
6 · The paper itself

Abstract

backgroundScreening over many years is required to optimize colorectal cancer (CRC) outcomes.

objectiveTo evaluate the effect of a CRC screening intervention on adherence to CRC screening over 9 years.

designRandomized trial.

settingIntegrated health care system in Washington state.

participantsBetween August 2008 and November 2009, 4653 adults in a Washington state integrated health care system aged 50-74 due for CRC screening were randomized to usual care (UC; N =1163) or UC plus study interventions (interventions: N = 3490).

interventionsYears 1 and 2: (arm 1) UC or this plus study interventions; (arm 2) mailed fecal tests or information on scheduling colonoscopy; (arm 3) mailings plus brief telephone assistance; or (arm 4) mailings and assistance plus nurse navigation. In year 3, stepped-intensity participants (arms 2, 3, and 4 combined) still eligible for screening were randomized to either stopped or continued interventions in years 3 and 5-9. MAIN MEASURES: Time in adherence to CRC testing over 9 years (covered time, primary outcome), and percent with no CRC testing in participants assigned to any intervention compared to UC only. Poisson regression models estimated incidence rate ratios for covered time, adjusting for patient characteristics and accounting for variable follow-up time. KEY

resultsCompared to UC, intervention participants had 21% more covered time over 9 years (57.5% vs. 69.1%; adjusted incidence rate ratio 1.21, 95% confidence interval 1.16-1.25, P<0.001). Fecal testing accounted for almost all additional covered time among intervention patients. Compared to UC, intervention participants were also more likely to have completed at least one CRC screening test over 9 years or until censorship (88.6% vs. 80.6%, P<0.001).

conclusionsAn outreach program that included mailed fecal tests and phone follow-up led to increased adherence to CRC testing and fewer age-eligible individuals without any CRC testing over 9 years.

trial registrationSystems of Support (SOS) to Increase Colon Cancer Screening and Follow-up (SOS), NCT00697047, clinicaltrials.gov/ct2/show/NCT00697047.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerAgedChildColonoscopyHumansMiddle AgedOccult BloodPostal Servicecolorectal cancerhealth care systemmailed fecal testsrandomized trialscreening

Identifiers

PMID34047921
PMCPMC8162159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.