Evidence map›Paper›PMID 34047876›Full record

ArticleExperimental & applied acarology2021

Deltamethrin resistant alleles predominate in Rhipicephalus sanguineus sensu lato in South India.

Anand Amrutha, Lakshmanan Bindu, T A Kajal, J Siju, T V Aravindakshan

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Article in Experimental & applied acarology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anand AmruthaSchool of Applied Animal Production and Biotechnology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala, 680651, India.ORCID http://orcid.org/0000-0002-7678-9082
Lakshmanan BinduDepartment of Veterinary Parasitology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala, 680651, India. bindul@kvasu.ac.in.ORCID http://orcid.org/0000-0002-5138-5620
T A KajalDepartment of Veterinary Parasitology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala, 680651, India.
J SijuDepartment of Veterinary Microbiology, College of Veterinary and Animal Sciences, Kerala Veterinary and Animal Sciences University, Mannuthy, Thrissur, Kerala, 680651, India.
T V AravindakshanSchool of Applied Animal Production and Biotechnology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala, 680651, India.
Kerala Veterinary and Animal Sciences University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brown dog tick, Rhipicephalus sanguineus sensu lato, an important ectoparasite transmitting several pathogens, is the most common tick species infesting dogs. Control of ticks being central to the control of fatal tick-borne diseases, this study attempted to assess the susceptibility/resistance of brown dog ticks to synthetic pyrethroids, the commonly used acaricides against ticks. Larval packet assay revealed 60% of isolates tested to be resistant and tolerant to deltamethrin as per the resistance factor that ranged from 1 to 53.7. Sequence analysis of the PCR amplified product of domain II S4-5 linker of sodium channel gene in R. sanguineus revealed novel polymorphisms, viz., C190A, G215T and T270C. In domain III S6 region of the gene, a T2134C mutation was observed. Genotyping with allele-specific PCR targeting domain II S4-5 linker region using single larvae revealed that most R. sanguineus larvae in the study population were homozygous resistant (RR) genotypes, followed by heterozygous (RS) and homozygous susceptible (SS) genotypes. A higher proportion of RS genotypes was also observed in domain III S6 region. This first report of genotyping of Indian R. sanguineus to analyse synthetic pyrethroid resistance highlights the need to devise alternate control strategies to reduce the brown dog tick population.

Indexed as

Dog DiseasesPyrethrinsRhipicephalusRhipicephalus sanguineusTick InfestationsAllelesAnimalsDogsIndiaNitrilesdecamethrinNitrilesPyrethrinsDeltamethrin resistanceIndiaRhipicephalus sanguineus

Identifiers

PMID34047876
OpenAlexW3164474676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.