Evidence map›Paper›PMID 34047857›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021

Megalencephaly-capillary malformation syndrome and associated hydrocephalus: treatment options and revision of the literature.

M Alamar, S Candela, A Flor-Goikoetxea, H Salvador, A F Martinez-Monseny, J Muchart, J Hinojosa

Abstract readReview
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In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

M AlamarNeurosurgery Department, Hospital Sant Joan de Déu, Passeig de Sant Joan de Déu s/n, 08950, Esplugues de Llobregat, Barcelona, Spain. malamar@sjdhospitalbarcelona.org.ORCID 0000-0002-4942-1717
S CandelaNeurosurgery Department, Hospital Sant Joan de Déu, Passeig de Sant Joan de Déu s/n, 08950, Esplugues de Llobregat, Barcelona, Spain.
A Flor-GoikoetxeaNeurosurgery Department, Hospital de La Ribera, Alzira, Spain.
H SalvadorOncology Department, Hospital Sant Joan de Déu, Barcelona, Spain.
A F Martinez-MonsenyClinical Genetics Department and Pediatric Institute of Rare Diseases (IPER), Hospital Sant Joan de Déu, Barcelona, Spain.
J MuchartRadiology Department, Hospital Sant Joan de Déu, Barcelona, Spain.
J HinojosaNeurosurgery Department, Hospital Sant Joan de Déu, Passeig de Sant Joan de Déu s/n, 08950, Esplugues de Llobregat, Barcelona, Spain.
Hospital Sant Joan de Déu Barcelona · ESHospital de La Ribera · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe describe our series of 4 patients with megalencephaly-capillary malformation syndrome (MCAP) and review the literature in order to assess the optimal treatment for the associated hydrocephalus.

methodsWe review our institutional series of hydrocephalus associated with MCAP and review the literature, analyzing the causes that could originate the hydrocephalus and the different types of treatments proposed for them.

resultsOf our patients treated with ventriculoperitoneal (VP) shunt, one suffered a surgical revision of the shunt and died due to a cranial trauma unrelated to her syndrome or the previous shunt surgery, and the other did not undergo surgical revisions until the end of her follow-up. Our patients treated with endoscopic third ventriculostomy (ETV) have improved their symptomatology and have not suffered of any complications related to the hydrocephalus after the ETV surgery.

conclusionsWe update the treatment of MCAP-associated hydrocephalus and propose ETV as a valid treatment, as it seems a safe procedure with a low rate of complications.

Indexed as

HydrocephalusMegalencephalyNeuroendoscopyThird VentricleFemaleHumansInfantRetrospective StudiesTreatment OutcomeVentriculoperitoneal ShuntVentriculostomyEndoscopic third ventriculostomy (ETV)HydrocephalusMacrocephaly-capillary malformation (M-CM)Megalencephaly-capillary malformation (MCAP)Ventriculoperitoneal shunt (VP shunt)

Identifiers

PMID34047857
OpenAlexW3165649749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.